perindopril

	What is the most important information I should know about perindopril?
	What is perindopril?
	What should I discuss with my healthcare provider before taking perindopril?
	How should I take perindopril?
	What happens if I miss a dose?
	What happens if I overdose?
	What should I avoid while taking perindopril?
	What are the possible side effects of perindopril?
	What other drugs will affect perindopril?
	Where can I get more information?
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Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Perindopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of perindopril.

Do not use salt substitutes or potassium supplements while taking perindopril, unless your doctor has told you to.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking perindopril. Drink plenty of water each day while you are taking this medication.

Perindopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.

Perindopril is used to treat high blood pressure (hypertension) and to prevent heart attack in people with coronary artery disease.

Perindopril may also be used for other purposes not listed in this medication guide.

Do not use this medication if you are allergic to perindopril or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before you take perindopril, tell your doctor if you have:

• kidney disease (or if you are on dialysis);
• liver disease;
• heart disease or congestive heart failure;
• diabetes; or
• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Perindopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

It is not known whether perindopril passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Take each dose with a full glass of water.

Perindopril can be taken with or without food.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking perindopril. Drink plenty of water each day while you are taking this medication.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking perindopril. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store perindopril at room temperature away from moisture and heat.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling extremely dizzy or light-headed, or fainting.

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of perindopril.

Do not use salt substitutes or potassium supplements while taking perindopril, unless your doctor has told you to.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• feeling light-headed, fainting;
• urinating more or less than usual, or not at all;
• fever, chills, body aches, flu symptoms;
• pale skin, easy bruising or bleeding;
• tired feeling, muscle weakness, and pounding or uneven heartbeats;
• swelling, rapid weight gain;
• chest pain; or
• jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

• cough, stuffy nose;
• muscle or joint pain;
• dizziness, drowsiness, headache;
• sleep problems (insomnia);
• diarrhea, upset stomach; or
• mild skin itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

Before taking perindopril, tell your doctor if you are taking any of the following drugs:

• gold injections to treat arthritis;
• lithium (Lithobid, Eskalith);
• a potassium supplement such as K-Dur, Klor-Con;
• salt substitutes that contain potassium; or
• a diuretic (water pill).

This list is not complete and there may be other drugs that can interact with perindopril. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Your pharmacist can provide more information about perindopril.