iloprost

Use iloprost inhalation exactly as directed by your doctor. Iloprost inhalation should only be used with the Prodose AAD system. Do not use iloprost inhalation with other types of nebulizers. If you do not understand your instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Iloprost inhalation may lower blood pressure which can lead to dizziness or fainting. Stand up slowly when getting out of a chair or bed. If you experience fainting or if your dizziness gets worse contact your doctor.

Iloprost is an synthetic prostacyclin. It works by opening blood vessels in the lungs.

Iloprost is used as an inhalant to treat pulmonary arterial hypertension.

Iloprost inhalation may also be used for purposes other than those listed in this medication guide.

Before taking this medication, tell your doctor if you have.

• liver disease;
• heart disease;
• kidney disease;
• low blood pressure;
• chronic obstructive pulmonary disease (COPD);
• asthma; or
• a chest cold or cough.

You may need a lower dose or special monitoring during therapy with iloprost inhalation.

Iloprost is in the FDA pregnancy category C. This means that it is not known whether iloprost will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Iloprost passes into breast milk in small amounts and may affect a nursing baby. Do not take iloprost without first talking to your doctor if you are breast-feeding a baby.

Use iloprost inhalation exactly as directed by your doctor. Iloprost inhalation should only be used with the Prodose AAD system. Do not use it with other types of nebulizers. If you do not understand the instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Iloprost inhalation may cause a lowering of blood pressure which can lead to dizziness or fainting. Stand up slowly when getting out of a chair or bed. If you experience fainting or if your dizziness gets worse contact your doctor.

Store iloprost inhalation at room temperature away from moisture and heat.

Use the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and use the next one as directed. Do not use a double dose of this medication.

An overdose of this medication is not likely to occur. If you do suspect an overdose, call an emergency room or poison control center.

Avoid items or activities that you know are allergens for you if they make your symptoms worse. Clean areas where dust or pet fur may aggravate your condition.

Do not stop taking iloprost inhalation until your doctor approves. It may be some time before you begin to notice effects from this medication.

Serious side effects from iloprost inhalation are not likely to occur. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat, swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may also occur. Continue to use iloprost inhalation and talk to your doctor if you experience

• dry mouth, nose, or throat after use;
• coughing or throat irritation;
• hoarseness or deepening of the voice;
• headache, dizziness, or lightheadedness;
• nausea;
• flushing; or
• jaw tightness or pain.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Before using this medication, tell your doctor and pharmacist about any other drugs you are taking including vitamins, minerals, and herbal products.

Your pharmacist has additional information about iloprost inhalation written for health professionals that you may read.

Iloprost inhalation is available with a prescription under the brand name Ventavis. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.