Antacids for gastroesophageal reflux disease (GERD)

Antacids are available without a prescription in liquid, chewable tablet, chewing gum, and dissolving tablet forms to be taken by mouth. Liquid antacids may relieve symptoms faster than other forms of antacids.

Antacids make stomach juices less acidic (neutralize stomach acid).

Antacids with alginic acid (such as Gaviscon) contain a foaming agent that floats on top of the stomach contents. This may help keep stomach juices from coming in contact with your esophagus.

Antacids that contain simethicone (such as Maalox Anti-Gas or Mylanta Gas) may break down gas bubbles in your stomach. This may help reduce burping that might push stomach acid into your esophagus.

For people with occasional, mild to moderate symptoms of gastroesophageal reflux disease (GERD), antacids are often all that is needed to control the symptoms.

Many doctors will recommend long-term use of antacids if they help relieve your GERD symptoms. Do not use antacids for more than 2 weeks unless you have talked with your doctor about taking them on a long-term basis.

Antacids do not work the same for everyone. For people with occasional, mild to moderate heartburn, antacids may work very well. For people with severe GERD, antacids alone are unlikely to help.

A single dose of antacid often relieves heartburn for about an hour.

The active ingredients in antacids vary, with the following cautions for each:

• Calcium carbonate can cause constipation in some people. It can also stimulate acid rebound in some people. Acid rebound occurs when taking antacids causes the stomach to produce even more acid, making heartburn worse.
• Magnesium-containing antacids can cause diarrhea. If used too often by people who have kidney problems, antacids containing magnesium can lead to too much magnesium in the blood.
• Aluminum-containing antacids can cause constipation. If used too often by people with chronic kidney failure, antacids containing aluminum can lead to too much aluminum in the blood.

Many antacid preparations combine active ingredients to balance side effects. For example, antacids may contain both magnesium and aluminum to prevent diarrhea or constipation.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

Antacids are a simple and inexpensive treatment for heartburn. They are often useful for treating mild GERD or occasional heartburn. Most doctors recommend taking antacids as part of home treatment.

Antacids are taken in varying doses depending on their strength. They take effect within an hour, but their effect usually lasts only a short time compared with other medicines for GERD.

Lifestyle changes and antacids are usually tried first to treat pregnant women who have GERD. Antacids are safe to use for heartburn symptoms during pregnancy. If lifestyle changes and antacids don't help control your symptoms, talk to your doctor about using other medicines. Most of the time, symptoms get better after the baby is born.

Antacids that contain calcium carbonate (such as Rolaids or Tums) may also help boost calcium intake in women who are concerned about developing osteoporosis.

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