Imiquimod (Aldara) for warts

Imiquimod is a form of immunotherapy. Immunotherapy triggers your immune system to fight the virus causing the wart. This may destroy or shrink the wart.

Imiquimod is thought to work by helping the body's immune system fight viruses, including the human papillomavirus (HPV) that causes warts. It also may shrink the warts.

Imiquimod has been approved for use on genital warts and can be used for difficult-to-treat common warts. It may be used at home after a health professional teaches you how to apply it.

Whether imiquimod is an effective treatment for common warts is not yet known. It does appear to be effective in curing genital warts.¹

Common side effects of imiquimod include:

• Itching.
• Burning.
• Blistering.
• Scaling.
• Lightening of skin color.

Less common possible side effects include:

• Headache.
• Flu-like symptoms.
• Muscle pain.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

It is not known whether imiquimod is safe to use during pregnancy or on children younger than 12.

Wash your hands after applying imiquimod cream, because it may cause skin irritation.

Imiquimod may be used on warts that are resistant to other treatments. It is generally used when other treatments have failed.

Imiquimod treatment is expensive.

Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

Citations

1. Wiley DJ (2003). Genital warts. Clinical Evidence (9): 1741–1753.