National Organization for Rare Disorders, Inc.
- CCM Syndrome
- Rib Gap Defects with Micrognathia
Cerebrocostomandibular syndrome is an extremely rare inherited disorder characterized by an abnormally small jaw (micrognathia), malformations of the roof of the mouth (palate), improper positioning of the tongue (glossoptosis), and abnormal development of the ribs (rib dysplasia). In most cases, such abnormalities contribute to respiratory problems (insufficiency) during early infancy. Although some affected individuals have normal intelligence, others exhibit moderate to severe mental retardation. Although research suggests that cerebrocostomandibular syndrome is usually inherited as an autosomal recessive genetic trait, some cases have also been documented in the medical literature that suggest autosomal dominant inheritance.
1825 K Street NW, Suite 1200
Washington, DC 20006
American Speech-Language-Hearing Association
2200 Research Boulevard
Rockville, MD 20850-3289
Cleft Palate Foundation
1504 East Franklin Street
Chapel Hill, NC 27514-2820
22 Ingersoll Road
P.O. Box 920554
Wellesley, MA 02181
NIH/National Heart, Lung and Blood Institute
P.O. Box 30105
Bethesda, MD 20892-0105
NIH/National Institute on Deafness and Other Communication Disorders
31 Center Drive, MSC 2320
Bethesda, MD 20892-3456
P.O. Box 5153
Stockton, CA 95205-0153
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
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Last Updated: 4/25/2008
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