doxorubicin liposomal

doxorubicin liposomal

Pronunciation: DOZ oh ROO bi sin LYE poe SOE mal

Brand: Doxil, Lipodox, Lipodox 50

What is the most important information I should know about doxorubicin liposomal?

Doxorubicin liposomal is a cancer medication.

Doxorubicin liposomal may increase the risk of heart or liver problems. Before you receive doxorubicin liposomal, tell your doctor if you have heart or liver disease.

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Doxorubicin liposomal can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).

Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

What is doxorubicin liposomal?

Doxorubicin liposomal is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Doxorubicin liposomal is used to treat ovarian cancer, AIDS-related Kaposi's sarcoma, and multiple myeloma.

Doxorubicin liposomal may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving doxorubicin liposomal?

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You should not use this medication if you are allergic to doxorubicin.

To make sure doxorubicin liposomal is safe for you, tell your doctor if you have:

  • kidney or liver disease;
  • heart disease; or
  • bone marrow suppression.

Tell your doctor about all other cancer medicines or radiation treatments you have received in the past.

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FDA pregnancy category D. Do not use doxorubicin liposomal if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medication and for at least a few months after your treatment ends.

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It is not known whether doxorubicin liposomal passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How is doxorubicin liposomal given?

Doxorubicin liposomal is injected into a vein through an IV. A healthcare provider will give you this injection.

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Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when doxorubicin liposomal is injected.

If this medicine accidentally gets on your skin, wash it thoroughly with soap and warm water.

Doxorubicin liposomal can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.

Chemotherapy can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). Patients or caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your doxorubicin liposomal injection.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while using doxorubicin liposomal?

Do not receive a "live" vaccine while using doxorubicin liposomal. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

What are the possible side effects of doxorubicin liposomal?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

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Call your doctor at once if you have:

  • pain, redness, swelling, blistering, or peeling skin on your hands or feet;
  • feeling short of breath (even with mild exertion), swelling, rapid weight gain;
  • fever, chills, body aches, flu symptoms;
  • white patches or sores inside your mouth or on your lips;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; or
  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating.

Doxorubicin liposomal may cause your urine to turn a reddish-orange color. This side effect by itself is usually not harmful. However, call your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).

Common side effects may include:

  • tired feeling;
  • loss of appetite, nausea, vomiting;
  • constipation, diarrhea; or
  • temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect doxorubicin liposomal?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with doxorubicin liposomal, especially:

  • cyclophosphamide; or
  • mercaptopurine.

This list is not complete. Other drugs may interact with doxorubicin liposomal, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your doctor or pharmacist can provide more information about doxorubicin liposomal.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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