enzalutamide

enzalutamide

Pronunciation: ENZ a LOOT a mide

Brand: Xtandi

What is the most important information I should know about enzalutamide?

Multum nopreg

Although not for use by women, enzalutamide can cause birth defects if the mother or the father is taking this medicine. Use a condom and one other form of birth control to prevent pregnancy during your treatment, and for at least 3 months after your treatment ends.

Enzalutamide can increase your risk of having a seizure. Tell your doctor if you have a history of seizures, or if you have recently had a head injury, stroke, or brain tumor. Also tell your doctor about all medicines you use.

Multum calldoc

Enzalutamide may cause side effects on your spinal cord. Stop taking this medicine and call your doctor at once if you have severe low back pain, trouble walking or standing up, pain or weakness in your lower body, severe and worsening numbness or tingling, or sudden loss of bladder or bowel control.

What is enzalutamide?

Enzalutamide is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones).

Enzalutamide is used to treat prostate cancer.

Enzalutamide may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking enzalutamide?

Enzalutamide can increase your risk of having a seizure. To make sure this medicine is safe for you, tell your doctor if you have:

  • a history of seizures or epilepsy; or
  • a recent head injury, stroke, or brain tumor (in the past 12 months).
Multum nopreg

FDA pregnancy category X. Although not for use by women, enzalutamide can cause birth defects if the mother or the father is taking this medicine. Do not use enzalutamide if you are pregnant.

If you are taking enzalutamide and your sexual partner could become pregnant, use a condom and one other form of birth control to prevent pregnancy during treatment. Keep using these birth control methods for at least 3 months after your treatment ends. Tell your doctor at once if a pregnancy occurs while either parent is being treated with enzalutamide.

Multum nobrfeed

Although this medicine is not for use by women, it is not known whether enzalutamide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How should I take enzalutamide?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take enzalutamide with or without food. Take the medicine at the same time each day.

Multum nocrush

Do not crush, break, or dissolve a enzalutamide capsule. Swallow it whole.

Prostate cancer is sometimes treated with a combination of drugs. Use all medications as directed by your doctor. Do not change your doses or medication schedule without your doctor's advice.

Multum rt

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose if you remember it later in the day. Skip the missed dose if it is almost time for your next day's dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking enzalutamide?

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This medication can make you dizzy, and may cause you to have a seizure or suddenly become unconscious. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of enzalutamide?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum calldoc

Stop using enzalutamide and call your doctor at once if you have:

  • seizure (black-out or convulsions);
  • severe low back pain, trouble walking or standing up;
  • pain or weakness in your lower body, severe and worsening numbness or tingly feeling;
  • sudden loss of bladder or bowel control;
  • fever, cough with yellow or green mucus, stabbing chest pain, wheezing, feeling short of breath;
  • red or pink urine; or
  • increased blood pressure (severe headache, blurred vision, buzzing in your ears, confusion, chest pain, uneven heartbeats).

Common side effects may include:

  • anxiety, dizziness, headache, sleep problems (insomnia);
  • feeling weak or tired;
  • back pain, joint or muscle pain, muscle weakness;
  • flushing (warmth, redness, hot feeling);
  • numbness, burning pain, or prickly feeling under your skin;
  • swelling in your hands or feet;
  • diarrhea; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect enzalutamide?

Enzalutamide can increase your risk of having a seizure. This effect may be more likely if you also use certain other medicines that increase seizure risk. Tell your doctor if you are using an antibiotic, an antidepressant, asthma medication (bronchodilator), birth control pills or hormone replacement, insulin or oral diabetes medicine, a steroid, or medicine to treat mental illness.

Many drugs can interact with enzalutamide. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with enzalutamide, especially:

  • gemfibrozil;
  • quinidine;
  • alfentanil, fentanyl;
  • dihydroergotamine, ergotamine;
  • a blood thinner such as warfarin, Coumadin;
  • herbal products--echinacea, St. John's wort;
  • HIV/AIDS medication--efavirenz, etravirine, nevirapine, ritonavir;
  • medicine for narcolepsy--armodafinil, modafinil;
  • medicine to prevent organ transplant rejection--cyclosporine, sirolimus, tacrolimus;
  • seizure medication--carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone, rufinamide; or
  • tuberculosis medication--rifampin.

This list is not complete and many other drugs can interact with enzalutamide. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about enzalutamide.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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