paricalcitol

paricalcitol

Pronunciation: PAR i KAL si tol

Brand: Zemplar

Zemplar 1 mcg

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Zemplar 2 mcg

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Zemplar 4 mcg

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What is the most important information I should know about paricalcitol?

Multum donot

Do not use this medication if you have ever had an allergic reaction to vitamin D, or if you have high levels of calcium or vitamin D in your blood.

Before taking paricalcitol, tell your doctor if you have high blood pressure, liver disease, or an electrolyte imbalance.

Multum donot

Do not take other vitamin or mineral supplements unless your doctor has told you to.

Avoid using calcium supplements or antacids without your doctor's advice. Use only the specific type of supplement or antacid your doctor recommends. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

While using paricalcitol, you may need blood tests at your doctor's office. Visit your doctor regularly.

Multum emt

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamin D can cause serious or life-threatening side effects.

Overdose symptoms may include headache, weakness, drowsiness, dry mouth, nausea, vomiting, constipation, muscle or bone pain, metallic taste in the mouth, weight loss, itchy skin, changes in heart rate, loss of interest in sex, confusion, unusual thoughts or behavior, feeling unusually hot, severe pain in your upper stomach spreading to your back, or fainting.

Paricalcitol is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you must eat or avoid to help control your condition.

What is paricalcitol?

Paricalcitol is a man-made form of vitamin D. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Paricalcitol is used to treat or prevent hyperparathyroidism (overactive parathyroid gland) in people with chronic kidney failure.

Paricalcitol may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking paricalcitol?

Multum donot

Do not use this medication if you have ever had an allergic reaction to vitamin D, or if you have:

  • high levels of calcium in your blood (hypercalcemia); or
  • high levels of vitamin D in your body (vitamin D toxicity).

If you have any of these other conditions, you may need a paricalcitol dose adjustment or special tests:

  • high blood pressure;
  • liver disease; or
  • an electrolyte imbalance.
Multum nopreg

FDA pregnancy category C. It is not known whether paricalcitol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication..

Your paricalcitol dose needs may change if you are breast-feeding a baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take paricalcitol?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Paricalcitol is sometimes taken daily, and sometimes taken every other day. Follow your doctor's instructions carefully.

Your doctor may occasionally change your dose to make sure you get the best results.

You may take this medication with or without food.

While using paricalcitol, you may need blood tests at your doctor's office. Visit your doctor regularly.

Paricalcitol is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you must eat or avoid to help control your condition.

Multum rt

Store at room temperature away from moisture, light, and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of vitamin D can cause serious or life-threatening side effects.

Overdose symptoms may include headache, weakness, drowsiness, dry mouth, nausea, vomiting, constipation, muscle or bone pain, metallic taste in the mouth, weight loss, itchy skin, changes in heart rate, loss of interest in sex, confusion, unusual thoughts or behavior, feeling unusually hot, severe pain in your upper stomach spreading to your back, or fainting.

What should I avoid while taking paricalcitol?

Multum donot

Do not take other vitamin or mineral supplements unless your doctor has told you to.

Avoid using calcium supplements or antacids without your doctor's advice. Use only the specific type of supplement or antacid your doctor recommends.

What are the possible side effects of paricalcitol?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Stop taking paricalcitol and call your doctor at once if you have a serious side effect such as:

  • fever, chills, body aches, flu symptoms;
  • chest pain, feeling short of breath;
  • feeling like you might pass out;
  • swelling, rapid weight gain;
  • pain or burning when you urinate;
  • dry mouth, drowsiness, increased urination, fast heart rate, feeling light-headed, fainting, or seizure (convulsions);
  • nausea, loss of appetite, increased thirst, muscle weakness, confusion, and feeling tired or restless;
  • early signs of vitamin D overdose (weakness, metallic taste in your mouth, weight loss, muscle or bone pain, constipation, nausea, and vomiting).

Less serious side effects may include:

  • dizziness, spinning sensation;
  • back pain, mild muscle or joint pain;
  • stomach pain, indigestion;
  • diarrhea;
  • sore throat, cough, runny or stuffy nose; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect paricalcitol?

Tell your doctor about all other medicines you use, especially:

  • cholestyramine (Prevalite, Questran);
  • conivaptan (Vaprisol);
  • digoxin (Lanoxin);
  • imatinib (Gleevec);
  • isoniazid (for treating tuberculosis);
  • an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);
  • antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);
  • an antidepressant such as nefazodone;
  • heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others; or
  • HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir).

This list is not complete and other drugs may interact with paricalcitol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about paricalcitol.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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