quetiapine

quetiapine

Pronunciation: kwe TYE a peen

Brand: SEROquel, SEROquel XR

Quetiapine 100 mg-APO

round, yellow, imprinted with APO, QUE 100

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Quetiapine 200 mg-APO

round, white, imprinted with APO, QUE 200

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Quetiapine 25 mg-APO

round, pink, imprinted with APO, QUE 25

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Quetiapine 300 mg-APO

capsule, white, imprinted with APO, QUE 300

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Quetiapine 400 mg-APO

capsule, yellow, imprinted with APO, QUE 400

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Quetiapine 50 mg-APO

round, white, imprinted with APO, QUE 50

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Seroquel 100 mg

round, yellow, imprinted with SEROQUEL 100

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Seroquel 200 mg

round, white, imprinted with SEROQUEL 200

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Seroquel 25 mg

round, peach, imprinted with SEROQUEL 25

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Seroquel 300 mg

oblong, white, imprinted with SEROQUEL, 300

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Seroquel 400 mg

oblong, yellow, imprinted with SEROQUEL, 400

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Seroquel 50 mg

round, white, imprinted with SEROQUEL 50

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What is the most important information I should know about quetiapine?

Multum emt

Never take quetiapine in larger amounts, or for longer than recommended by your doctor. High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include tremors or other uncontrollable muscle movements.

Multum donot

Quetiapine is not for use in psychotic conditions related to dementia. Quetiapine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Multum emt

Stop using quetiapine and call your doctor at once if you have the following symptoms: very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, uncontrolled muscle movements, feeling light-headed, blurred vision, eye pain, increased thirst and urination, excessive hunger, fruity breath odor, weakness, nausea and vomiting.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

What is quetiapine?

Quetiapine is an antipsychotic medicine. It works by changing the actions of chemicals in the brain.

Quetiapine is used to treat schizophrenia in adults and children who are at least 13 years old.

Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old.

Quetiapine is also used together with antidepressant medications to treat major depressive disorder in adults.

Multum nochild

Extended-release quetiapine (Seroquel XR) is for use only in adults and should not be given to anyone younger than 18 years old.

Quetiapine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking quetiapine?

Multum donot

Quetiapine is not for use in psychotic conditions related to dementia. Quetiapine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

To make sure you can safely take quetiapine, tell your doctor if you have any of these other conditions:

  • liver or kidney disease;
  • heart disease, high blood pressure, heart rhythm problems, a history of heart attack or stroke;
  • a history of low white blood cell (WBC) counts;
  • a thyroid disorder;
  • seizures or epilepsy;
  • cataracts;
  • high cholesterol or triglycerides;
  • a personal or family history of diabetes; or
  • trouble swallowing.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Multum nopreg

FDA pregnancy category C. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

Quetiapine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using quetiapine.

Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking quetiapine, do not stop taking it without your doctor's advice.

Multum nochild

Do not give quetiapine to a child without a doctor's advice. Extended-release quetiapine (Seroquel XR) is for use only in adults and should not be given to anyone younger than 18 years old.

How should I take quetiapine?

Multum emt

Never take quetiapine in larger amounts, or for longer than recommended by your doctor. High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include tremors or other uncontrollable muscle movements.

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Multum water

Take this medicine with a full glass of water. You may take quetiapine with or without food.

Multum nocrush

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking the pill may cause too much of the drug to be released at one time.

Quetiapine may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking quetiapine.

Multum emt

This medication can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking quetiapine.

Multum rt

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of quetiapine can be fatal. Overdose symptoms may include extreme drowsiness, fast heart rate, feeling light-headed, or fainting.

What should I avoid while taking quetiapine?

Multum dizzy

Quetiapine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid becoming overheated or dehydrated during exercise and in hot weather. You may be more prone to heat stroke.

Multum noalcohol

Avoid drinking alcohol. It can increase certain side effects of quetiapine.

What are the possible side effects of quetiapine?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Multum donot

Stop using quetiapine and call your doctor at once if you have a serious side effect such as:

  • very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors;
  • feeling like you might pass out;
  • jerky muscle movements you cannot control, trouble swallowing, problems with speech;
  • tremors, or restless muscle movements in your eyes, tongue, jaw, neck, arms, or legs;
  • mask-like appearance of the face, trouble swallowing, problems with speech;
  • blurred vision, eye pain, or seeing halos around lights;
  • increased thirst and urination, excessive hunger, fruity breath odor, weakness, nausea and vomiting; or
  • fever, chills, body aches, flu symptoms, white patches or sores inside your mouth or on your lips.

Less serious side effects may include:

  • dizziness, drowsiness, tired feeling;
  • dry mouth, sore throat;
  • stomach pain, upset stomach, nausea, vomiting, constipation;
  • breast swelling or discharge;
  • missed menstrual periods; or
  • increased appetite, weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect quetiapine?

Multum dizzy

Before using quetiapine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by quetiapine.

Tell your doctor about all other medicines you use, especially:

  • a medication to treat high blood pressure or a heart condition;
  • medications to treat Parkinson's disease;
  • steroids (prednisone and others);
  • an antibiotic or antifungal medication such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), ketoconazole (Nizoral), rifampin (Rifadin, Rimactane, Rifater), and others;
  • anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam);
  • heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), and others;
  • medications to treat HIV or AIDS;
  • migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig);
  • narcotic medication such as methadone (Methadose, Diskets, Dolophine);
  • seizure medication such as carbamazepine (Carbatrol, Tegretol), divalproex (Depakote), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), or valproic acid (Depakene, Stavzor); or
  • other antidepressant or medicines to treat psychiatric disorders, such as amitriptylline (Elavil, Vanatrip, Limbitrol), clozapine (FazaClo, Clozaril), fluoxetine (Prozac, Sarafem, Symbyax), haloperidol (Haldol), risperidone (Risperdal), thioridazine (Mellaril), and others.

This list is not complete and other drugs may interact with quetiapine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about quetiapine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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