Multiple Sclerosis: Medicines for Muscle Stiffness and Tremors
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Often a combination of these medicines given in small doses is better tolerated and more effective than a larger dose of a single medicine.
Some forms of natural or man-made substances related to marijuana, called cannabinoids, may help relieve spasticity.
Carbamazepine (Tegretol), which is a seizure medicine, benzodiazepines such as diazepam (Valium) and clonazepam (Klonopin), and beta-blockers, especially propranolol (Inderal), may have some benefit in treating tremors caused by MS.
Severe tremors are very hard to treat. If they do not respond to medicine, surgery may be needed.
The U.S. Food and Drug Administration (FDA) has issued a warning on seizure medicines and the risk of suicide and suicidal thoughts. The FDA does not recommend that people stop using these medicines. Instead, people who take seizure medicine should be watched closely for warning signs of suicide . People who take seizure medicine and who are worried about this side effect should talk to a doctor.
- Simpson DM, et al. (2008). Assessment: Botulinum neurotoxin for the treatment of spasticity (and evidence-based review): Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology, 70(19): 1691-1698.
Other Works Consulted
- Yadav V, et al. (2014). Summary of evidence-based guideline: Complementary and alternative medicine in multiple sclerosis: Report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology, 82(12): 1083-1092.
Primary Medical Reviewer Adam Husney, MD - Family Medicine
Anne C. Poinier, MD - Internal Medicine
Specialist Medical Reviewer Karin M. Lindholm, DO - Neurology
Current as ofOctober 9, 2017
Current as of: October 9, 2017
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