Uremia (uremic syndrome) is a serious complication of chronic kidney disease and acute kidney injury (which used to be known as acute renal failure). It occurs when urea and other waste products build up in the body because the kidneys are unable to eliminate them. These substances can become poisonous (toxic) to the body if they reach high levels.
Prolonged or severe fluid buildup (edema) may make the uremic syndrome worse.
Uremic syndrome may affect any part of the body and can cause:
Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored.
Current as of: August 11, 2019
Author: Healthwise Staff
Medical Review: Anne C. Poinier MD - Internal Medicine
E. Gregory Thompson MD - Internal Medicine
Adam Husney MD - Family Medicine
Kathleen Romito MD - Family Medicine
Tushar J. Vachharajani MD, FASN, FACP - Nephrology
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