How It Is Done
A needle biopsy of the liver is done in a clinic or a hospital. When cirrhosis of the liver or a cancer is suspected, the biopsy may be done during a laparoscopy.
You will need to take off all or most of your clothes. You will be given a cloth or paper gown to use during the test.
Before the test, you may be given a sedative through a vein (IV) in your arm. The sedative will help you relax and stay still.
During the test
During the test, you will lie on your back with your right arm resting under or above your head and your head turned to your left. Your doctor may tap on your chest and belly to find your liver, or he or she may use ultrasound.
Your doctor will mark a spot between two of your right lower ribs where the biopsy needle will be inserted. The site will be cleaned with a special soap and draped with sterile towels. The doctor will give you a medicine (local anesthetic) to numb the area.
You may be asked to take a deep breath, blow all the air out, and then hold your breath while the biopsy needle is being inserted and withdrawn. This will take only a few seconds. Holding your breath lowers the chance that the needle will go in your lung since the lungs are very close to the liver. It is important to stay still during the few seconds it takes for the doctor to collect the tissue sample. The doctor may take another tissue sample from the same spot, but from a different angle.
As soon as the doctor removes the needle, you can breathe normally. A bandage will be put on the puncture site.
After the test
You will rest in bed and lie on your right side for 2 to 6 hours after the test. After the anesthetic wears off, you may feel a dull pain in your right shoulder.
You can go home if you have no problems after the test.
How long the test takes
The test generally takes 15 to 30 minutes.