Pronunciation: A due KAN ue mab

Brand: Aduhelm

What is the most important information I should know about aducanumab?

Aducanumab can cause temporary swelling or bleeding in the brain that usually clears up with time. This may cause no symptoms but can be serious. Call your doctor if you have headaches, dizziness, nausea, confusion, or vision changes.

What is aducanumab?

Aducanumab is used to treat people with Alzheimer's disease.

Aducanumab may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving aducanumab?

Aducanumab can cause a condition called Amyloid Related Imaging Abnormalities or "ARIA."

ARIA is a temporary swelling or small spots of bleeding in the brain that usually clears up with time. Your doctor may perform an MRI of your brain before you receive this medicine.

Tell your doctor if you are pregnant or breastfeeding.

How is aducanumab given?

Aducanumab is injected into a vein by a healthcare provider.

This medicine is injected slowly over 1 hour.

Aducanumab is usually given every 4 weeks, at least 21 days apart.

You will need occasional brain MRIs while receiving aducanumab.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid while receiving aducanumab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of aducanumab?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your care provider if you have a rash, trouble breathing, or swelling in your face.

Aducanumab can cause temporary swelling or bleeding in the brain. Call your doctor if you have:

  • headaches, dizziness, confusion;
  • nausea; or
  • vision changes.

Common side effects may include:

  • ARIA with symptoms, or with signs that appear on an MRI;
  • headache; or
  • falls.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect aducanumab?

Other drugs may affect aducanumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your pharmacist can provide more information about aducanumab.

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