barberry

What is the most important information I should know about barberry?

Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is barberry?

Barberry is an herb, also called Agracejo, Berberidis, Berbéris, Berberis, Berberitze, Berberry, Berbis, Épine-Vinette, Espino Cambrón, Jaundice Berry, Mountain Grape, Oregon Grape, Pipperidge, Piprage, Sauerdorn, Sow Berry, Vinettier, and other names. The fruit, bark, and roots of the barberry plant are used to make an herbal medicine.

Barberry has been used in alternative medicine as an aid in treating dental plaque (tartar), swollen gums (gingivitis), kidney or bladder problems, stomach cramps, bowel problems, gout, arthritis, circulation problems, and other conditions. However, the use of barberry in these conditions has not been proven with research to be effective.

Barberry is likely to be safe when consumed as a food. But the safety of using barberry as a medicine has not been proven with research.

Barberry is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Barberry may also be used for purposes not listed in this product guide.

What should I discuss with my healthcare provider before taking barberry?

Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to take barberry if you have:

• a bleeding or blood clotting disorder such as hemophilia;
• low blood pressure; or
• diabetes (barberry can lower your blood sugar).

How should I take barberry?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use barberry, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Barberry can affect blood-clotting and may increase your risk of bleeding. If you need surgery, dental work, or a medical procedure, stop taking barberry at least 2 weeks ahead of time.

What happens if I miss a dose?

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra barberry to make up the missed dose.

What happens if I overdose?

What should I avoid while taking barberry?

Avoid taking barberry with a cold medicine that contains an antihistamine (such as chlorpheniramine, diphenhydramine, or doxylamine).

• affect blood-clotting --angelica (dong quai), capsicum, clove, danshen, garlic, ginger, ginkgo, horse chestnut, panax ginseng, poplar, red clover, turmeric, and willow;
• lower your blood pressure --casein peptides, cat's claw, coenzyme Q-10, fish oil, L-arginine, lycium, stinging nettle, and others;
• lower your blood sugar --alpha-lipoic acid, chromium, devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others; or
• cause drowsiness --5-HTP (5-hydroxytryptophan), California poppy, catnip, chamomile, gotu kola, Jamaican dogwood, kava, melatonin, St. John's wort, skullcap (or scullcap), valerian, yerba mansa, and others.

What are the possible side effects of barberry?

• low blood sugar --headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect barberry?

Do not take barberry without medical advice if you are using a medication to treat any of the following conditions:

• any type of infection (including HIV, malaria, or tuberculosis);
• asthma or allergies;
• cancer;
• erectile dysfunction;
• heartburn or gastroesophageal reflux disease (GERD);
• high blood pressure, high cholesterol, or a heart condition;
• migraine headaches;
• overactive bladder;
• Parkinson's disease;
• psoriasis, rheumatoid arthritis, or other autoimmune disorders;
• a psychiatric disorder; or
• seizures.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with barberry, especially:

• a blood thinner (warfarin, Coumadin, Jantoven); or
• insulin or oral diabetes medicine.

This list is not complete. Other drugs may interact with barberry, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this product guide.

Where can I get more information?

Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.