What are the possible side effects of blinatumomab?
Some side effects may occur during the injection. Tell your caregiver right away if you feel weak, nauseated, light-headed, tired, chilled or feverish, or you have a headache, muscle pain, skin rash, wheezing, trouble breathing, or swelling in your face.
Get emergency medical help if you signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Also tell your caregivers or seek emergency medical attention if you have signs of life-threatening nerve problems, such as:
- slurred speech, confusion;
- problems with balance;
- a seizure (convulsions); or
- loss of consciousness.
A serious side effect of blinatumomab is called cytokine release syndrome (CRS). Tell your caregivers right away if you have signs of this condition: fever, chills, trouble breathing, body aches, vomiting, diarrhea, or feeling light-headed. Your caregivers will have medication available to quickly treat CRS if it occurs.
Call your doctor at once if you have:
- severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
- low potassium --leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling;
- low blood cell counts --fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
- signs of tumor cell breakdown --confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.
Common side effects may include:
- reactions during the injection;
- low blood cell counts;
- fever, infections; or
- headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.