How is brexucabtagene autoleucel given?
Brexucabtagene autoleucel is available only at an authorized hospital or clinic, and must be given by specially trained healthcare professionals.
Your care providers will use an intravenous (IV) needle to draw your blood for collecting the white blood cells. The cells are then frozen and sent to a laboratory where they are made into brexucabtagene autoleucel. Because it will take time to process your blood cells into brexucabtagene autoleucel, you will not receive the medicine on the same day your blood cells are drawn.
Beginning 5 days before this medicine is given, you will be pre-treated with chemotherapy to help prepare your body for brexucabtagene autoleucel.
About 30 to 60 minutes before you receive brexucabtagene autoleucel, you will be given other medications to help prevent serious side effects or allergic reaction.
Once your body is ready to receive brexucabtagene autoleucel, your care providers will inject the medicine as an infusion into a vein.
Your doctor will need to check your progress on a daily basis for at least 7 days after the infusion.
For at least 4 weeks, plan to stay near the hospital or clinic where you received brexucabtagene autoleucel.
Brexucabtagene autoleucel affects your immune system. You may get infections more easily, even serious or fatal infections.
If you've ever had hepatitis B, using brexucabtagene autoleucel can cause this virus to become active or get worse. You may need frequent liver function tests.
Brexucabtagene autoleucel can have long lasting effects on your body. You may need frequent medical tests while using this medicine and for a short time after your last dose.