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chlophedianol, phenylephrine, and pyrilamine

chlophedianol, phenylephrine, and pyrilamine

Pronunciation: KLOE fe DYE a nol, FEN il EFF rin, and pir IL a meen

Brand: Pro-Chlo

What is the most important information I should know about chlophedianol, phenylephrine, and pyrilamine?

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

What is chlophedianol, phenylephrine, and pyrilamine?

Chlophedianol is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Chlophedianol, phenylephrine, and pyrilamine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, bronchitis, or emphysema.

Chlophedianol, phenylephrine, and pyrilamine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking chlophedianol, phenylephrine, and pyrilamine?

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medicine if you are allergic to chlophedianol, phenylephrine, or pyrilamine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

  • any type of breathing disorder;
  • blockage in your intestines;
  • bladder obstruction or other urination problems;
  • cough with mucus;
  • glaucoma;
  • diabetes;
  • liver or kidney disease;
  • heart disease, high blood pressure;
  • a thyroid disorder; or
  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

FDA pregnancy category C. It is not known whether chlophedianol, phenylephrine, and pyrilamine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Chlophedianol, phenylephrine, and pyrilamine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

How should I take chlophedianol, phenylephrine, and pyrilamine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken a cough or cold medicine within the past few days.

Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Since cough or cold medicine is taken when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking chlophedianol, phenylephrine, and pyrilamine?

This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Ask a doctor or pharmacist before using any other cold, allergy, cough, or sleep medicine. Antihistamines, antitussives, and decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine, antitussive, or decongestant.

Drinking alcohol can increase certain side effects of chlophedianol, phenylephrine, and pyrilamine.

What are the possible side effects of chlophedianol, phenylephrine, and pyrilamine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • chests tightness, wheezing, shortness of breath;
  • severe drowsiness;
  • a light-headed feeling, like you might pass out;
  • little or no urinating;
  • severe dizziness or anxiety; or
  • severe restless feeling or being unable to sleep.

Common side effects may include:

  • mild dizziness or drowsiness;
  • dry mouth, nose, or throat;
  • diarrhea, constipation, upset stomach;
  • feeling restless or excited (especially in children);
  • blurred vision; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect chlophedianol, phenylephrine, and pyrilamine?

Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking chlophedianol, phenylephrine, and pyrilamine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Where can I get more information?

Your pharmacist can provide more information about chlophedianol, phenylephrine, and pyrilamine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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