cyclobenzaprine

What is the most important information I should know about cyclobenzaprine?

Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine.

What is cyclobenzaprine?

Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.

Cyclobenzaprine is used together with rest and physical therapy to relieve muscle spasms caused by painful conditions such as an injury.

Cyclobenzaprine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking cyclobenzaprine?

• a thyroid disorder;
• heart block, heart rhythm disorder, congestive heart failure; or
• if you have recently had a heart attack.

Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

Tell your doctor if you have ever had:

• liver disease;
• glaucoma;
• enlarged prostate; or
• problems with urination.

Older adults may be more sensitive to the effects of this medicine.

How should I take cyclobenzaprine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Cyclobenzaprine is usually taken once daily for only 2 or 3 weeks. Follow your doctor's dosing instructions very carefully.

Take the medicine at the same time each day.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations.

What should I avoid while taking cyclobenzaprine?

What are the possible side effects of cyclobenzaprine?

• fast or irregular heartbeats;
• chest pain or pressure, pain spreading to your jaw or shoulder; or
• sudden numbness or weakness (especially on one side of the body), slurred speech, balance problems.

Serious side effects may be more likely in older adults.

Common side effects may include:

• drowsiness, tiredness;
• headache, dizziness;
• dry mouth; or
• upset stomach, nausea, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect cyclobenzaprine?

Tell your doctor about all your other medicines, especially:

• bupropion (Zyban, for smoking cessation);
• meperidine;
• tramadol;
• verapamil;
• cold or allergy medicine that contains an antihistamine (Benadryl and others);
• medicine to treat Parkinson's disease;
• medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;
• medicine to treat overactive bladder; or
• bronchodilator asthma medication.

This list is not complete. Other drugs may affect cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about cyclobenzaprine.