diroximel fumarate

diroximel fumarate

[en Español]

diroximel fumarate

Pronunciation: dye ROX i mel FUE ma rate

Brand: Vumerity

What is the most important information I should know about diroximel fumarate?

You should not use this medicine if you have had a severe allergic reaction to diroximel fumarate, or if you also use dimethyl fumarate (Tecfidera).

What is diroximel fumarate?

Diroximel fumarate is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).

Diroximel fumarate may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking diroximel fumarate?

You should not use this medicine if:

  • you have had a severe allergic reaction to diroximel fumarate or dimethyl fumarate (Tecfidera); or
  • you also use dimethyl fumarate.

Tell your doctor if you have ever had:

  • liver disease;
  • kidney disease;
  • infections; or
  • low white blood cell (WBC) counts.

Tell your doctor if you are pregnant or breastfeeding.

Diroximel fumarate is not approved for use by anyone younger than 18 years old.

How should I take diroximel fumarate?

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using diroximel fumarate.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Swallow the capsule whole and do not crush, chew, break, or open it.

If you take diroximel fumarate with food, avoid foods that are high in calories or fat. Your meal or snack should not contain more than 700 calories or more than 30 grams of fat.

Do not drink alcohol when you take your diroximel fumarate dose.

Diroximel fumarate can lower your blood cell counts. You will need frequent medical tests, and your next dose may be delayed based on the results.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking diroximel fumarate?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of diroximel fumarate?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Diroximel fumarate may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.

Call your doctor at once if you have signs of liver problems, such as:

  • right-sided upper stomach pain;
  • loss of appetite;
  • tiredness;
  • dark urine; or
  • jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • indigestion, nausea, vomiting, stomach pain;
  • diarrhea; or
  • flushing (sudden warmth, redness, or tingly feeling);

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect diroximel fumarate?

Other drugs may affect diroximel fumarate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about diroximel fumarate.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2020 Cerner Multum, Inc. Version: 1.01. Revision date: 11/7/2019.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link .