doxepin topical

What is the most important information I should know about doxepin topical?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is doxepin topical?

Doxepin is a tricyclic antidepressant. When applied to the skin, this medicine can help relieve itching but it will not treat symptoms of depression.

Doxepin topical (for use on skin) is used to treat itchy skin in adults with eczema or other skin conditions that can lead to repeated scratching and thickened skin.

Doxepin topical may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using doxepin topical?

• untreated narrow-angle glaucoma; or
• urination problems.

Before using doxepin topical, tell your doctor about all your medical conditions or allergies.

How should I use doxepin topical?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Doxepin topical is usually applied 4 times each day. Allow at least 3 hours to pass between applications.

Apply a thin layer of medication to the affected skin and rub in gently.

Do not cover treated skin area with a bandage or plastic. Bandaging can increase the amount of drug absorbed through your skin and may cause harmful effects.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Serious overdose symptoms can occur if too much of this medicine is absorbed through your skin. Overdose symptoms may include extreme dizziness or drowsiness, feeling hot or cold, vomiting, confusion, agitation, trouble concentrating, irregular heartbeats, hallucinations, fainting, dilated pupils, muscle stiffness, or seizure (convulsions).

What should I avoid while using doxepin topical?

What are the possible side effects of doxepin topical?

Although the risk of serious side effects is low when doxepin topical is applied to the skin, side effects can occur if the medicine is absorbed into your bloodstream. You may feel drowsy after applying this medicine, especially if you have treated large areas of skin.

• severe drowsiness;
• confusion;
• severe dry mouth;
• painful or difficult urination;
• blurred vision; or
• new or worsening skin symptoms.

Some side effects may be more likely in older adults.

Common side effects may include:

• burning or stinging where the medicine was applied;
• mild drowsiness; or
• dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect doxepin topical?

Before using doxepin topical, tell your doctor if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor about all your current medicines and any you start or stop using, especially:

• cimetidine;
• heart rhythm medication; or
• any antidepressant medication you take by mouth.

This list is not complete. Other drugs may interact with doxepin topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about doxepin topical.