ecallantide

Pronunciation: e KAL an tide

Brand: Kalbitor

What is the most important information I should know about ecallantide?

Ecallantide can cause a serious allergic reaction within 1 hour after injection. Symptoms include wheezing, cough, trouble breathing or swallowing, itching, hives, dizziness, fainting, or swelling in your face or throat.

What is ecallantide?

Ecallantide is used to treat attacks of hereditary angioedema (an immune system disorder). This medicine is for use in adults and children at least 12 years old.

Ecallantide is not a cure for hereditary angioedema.

Ecallantide may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving ecallantide?

If possible during an emergency, tell your caregivers you have any type of allergy. Make sure any follow-up doctor knows you received this medicine.

You should not be treated with ecallantide if you are allergic to it.

If possible during an emergency, tell your caregivers if you are pregnant or breastfeeding.

How is ecallantide given?

Ecallantide is injected under the skin by a healthcare provider, usually in 3 separate injections.

You will be watched closely to make sure you do not have an allergic reaction to the medication.

If you still have angioedema symptoms after 3 injections, more may be given within 24 hours.

What happens if I miss a dose?

In a medical setting you are not likely to miss a dose.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid after receiving ecallantide?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of ecallantide?

Ecallantide can cause a serious allergic reaction within 1 hour after injection. Tell your caregivers right away if you have:

  • chest pain or tightness, fast or weak heartbeat;
  • wheezing, cough, throat irritation, trouble breathing;
  • hoarse voice, tight feeling in your throat, trouble swallowing;
  • swelling of your lips, tongue, or throat;
  • swelling or redness in your face;
  • itching, rash, or hives;
  • flushing (warmth, redness, or tingly feeling);
  • sneezing, runny or stuffy nose; or
  • dizziness, feeling like you might pass out.

An allergic reaction may have the same symptoms as hereditary angioedema. Your caregivers will watch you closely and will quickly treat an allergic reaction.

Common side effects may include:

  • headache;
  • nausea, diarrhea;
  • fever;
  • stuffy nose, sore throat; or
  • skin reactions where the medicine was injected (redness, rash, itching, bruising, swelling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ecallantide?

Other drugs may affect ecallantide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your doctor or pharmacist can provide more information about ecallantide.

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