This medication can harm an unborn baby or a nursing baby. Do not take ergotamine if you are pregnant or breast-feeding.
Do not take this medication if you are allergic to ergotamine or other ergot medicines, or if you have a history of heart disease, angina (chest pain), blood circulation problems, history of a heart attack or stroke, coronary artery disease, uncontrolled high blood pressure, severe liver or kidney disease, or a serious infection.
Using certain medications together with ergotamine can cause even greater decreases in blood flow than ergotamine used alone, which can lead to dangerous side effects. Tell your doctor about all other medications you are using.
Also tell your doctor about all of your medical conditions, especially high blood pressure, liver or kidney disease, or risk factors for coronary artery disease (diabetes, high blood pressure or cholesterol, menopause or hysterectomy, smoking, taking birth control pills, being overweight, having a family history of coronary artery disease, or being a man older than 40).
This medication will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.
Never take more than your prescribed dose of ergotamine. An overdose can be fatal.
Ergotamine is in a group of drugs called ergot alkaloids (ER-got AL-ka-loids). It works by narrowing the blood vessels around the brain. Ergotamine also affects blood flow patterns that are associated with certain types of headaches.
Ergotamine is used to treat a migraine type headache.
This medication will only treat a headache that has already begun. It will not prevent migraine headaches or reduce the number of attacks.
Ergotamine should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.
Ergotamine may also be used for purposes not listed in this medication guide.
Do not take this medication if you are allergic to ergotamine or similar medications such as Cafergot, D.H.E. 45, Migergot, Migranal, or Methergine.
Do not take ergotamine if you are pregnant or breast-feeding, or if you have:
Using certain medications together with ergotamine can cause even greater decreases in blood flow than ergotamine used alone, which can lead to dangerous side effects. Do not take ergotamine if you are also using any of the following medications:
Ergotamine can cause rare but serious side effects on the heart, including heart attack or stroke. To make sure you can safely take ergotamine, tell your doctor if you have any of these other conditions:
FDA pregnancy category X. Ergotamine can cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
Ergotamine can pass into breast milk and may harm a nursing baby. Ergotamine may also decrease milk production. Do not use if you are breast-feeding a baby.
Take exactly as prescribed by your doctor. Never take more than your prescribed dose of ergotamine. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks. Ergotamine is not for daily use.
Take the first dose of ergotamine as soon as you notice headache symptoms, or after an attack has already begun. Place 1 ergotamine tablet under your tongue.
If your headache does not completely go away, you may take a second tablet after at least 30 minutes have passed, and a third tablet if needed after another 30 minutes have passed (a total of 3 tablets).
If you still have migraine symptoms after taking a total of 3 tablets, call your doctor. Do not take more than a total of 3 tablets in any 24-hour period. Do not take more than a total of 5 tablets over a period of 7 days.
Do not give this medication to anyone else, even if they have the same headache symptoms you have. Ergotamine can be dangerous if it is used to treat headache in a person who has not been diagnosed by a doctor as having true migraine headaches.
Store at room temperature away from moisture, heat, and light. Do not take any stored ergotamine if the expiration date on the label has passed.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of ergotamine can be fatal.
Overdose can cause vomiting, confusion, drowsiness, weak pulses in your arms and legs, numbness and tingling or pain in your hands or feet, blue-colored fingers or toes, fainting, and seizure (convulsions).
Do not take ergotamine within 24 hours before or after using another migraine headache medicine, including:
Grapefruit and grapefruit juice may interact with ergotamine and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking ergotamine and call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Many drugs can interact with ergotamine. Below is just a partial list. Talk with your doctor before taking ergotamine if you are also taking:
This list is not complete and other drugs may interact with ergotamine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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