finerenone

Pronunciation: fin ER e none

Brand: Kerendia

What is the most important information I should know about finerenone?

Tell your doctor about all your other medicines. Some drugs should not be used with finerenone.

What is finerenone?

Finerenone is used in adults with chronic kidney disease related to diabetes mellitus type 2, to reduce the risk of:

  • kidney problems getting worse;
  • a heart attack;
  • needing to be hospitalized for heart failure; or
  • death from heart failure.

Finerenone may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking finerenone?

You should not use finerenone if you are allergic to it, or if you have problems with your adrenal gland.

Some drugs should not be used with finerenone. Your treatment plan may change if you also use:

  • nefazodone;
  • an antibiotic --clarithromycin, telithromycin;
  • antifungal medicine --itraconazole, ketoconazole, posaconazole, voriconazole; or
  • antiviral medicine for HIV or hepatitis C --boceprevir, cobicistat, dasabuvir, elvitegravir, indinavir, lopinavir/ritonavir, nelfinavir, ombitasvir, paritaprevir saquinavir, telaprevir, tipranavir.

Tell your doctor if you have ever had:

  • severe liver disease; or
  • high blood levels of potassium (hyperkalemia).

It is not known if finerenone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using this medicine, and for at least 1 day after your last dose.

Not approved for use by anyone younger than 18 years old.

How should I take finerenone?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take finerenone with or without food.

If you cannot swallow a tablet whole, crush the tablet and mix it with water or soft food such as applesauce. Swallow the mixture right away.

You will need medical tests.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not take 2 doses in one day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking finerenone?

Do not take potassium supplements or use salt substitutes, unless your doctor has told you to.

Grapefruit may interact with finerenone and cause side effects. Avoid consuming grapefruit products.

What are the possible side effects of finerenone?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • high blood potassium --nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or
  • low blood sodium --headache, confusion, problems with thinking or memory, weakness, feeling unsteady.

Common side effects may include:

  • high potassium;
  • low sodium; or
  • low blood pressure.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect finerenone?

Many drugs can affect finerenone, and some drugs should not be used at the same time. Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about finerenone.

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