Pronunciation: GAD oh DYE a mide

Brand: Omniscan, Omniscan Prefill Plus

What is the most important information I should know about gadodiamide?

Gadodiamide can cause a life-threatening condition in people with advanced kidney disease. Before receiving this medicine, tell your doctor if you have kidney disease or if you are on dialysis. You may not be able to receive gadodiamide. Also tell your doctor if you have recently received any contrast agents similar to gadodiamide.

What is gadodiamide?

Gadodiamide is a contrast agent that produces magnetic effects. It is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.

Gadodiamide is used to help diagnose certain disorders of the brain and spine (central nervous system), or the stomach and chest areas.

Gadodiamide may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving gadodiamide?

Gadodiamide can cause a life-threatening condition in people with advanced kidney disease. You should not receive this medication if you have kidney disease or if you are on dialysis.

You should not receive gadodiamide if you are allergic to it.

To make sure gadodiamide is safe for you, tell your doctor if you have ever had:

  • any type of reaction to a contrast agent;
  • diabetes;
  • high blood pressure;
  • liver disease;
  • asthma, hay fever, food or drug allergies;
  • an injury, surgery, or severe infection; or
  • if you are over 60 years old.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether gadodiamide passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

How is gadodiamide given?

Gadodiamide is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting during your MRI.

Your doctor or other healthcare provider may want to watch you for a short time after your test is over. This is to make sure you do not have any unwanted side effects or delayed reactions.

Gadodiamide can cause unusual results with certain medical for 12 to 24 hours after your MRI. Tell any doctor who treats you that you have received gadodiamide.

What happens if I miss a dose?

Since gadodiamide is used only during your MRI, you will not be on a dosing schedule.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving gadodiamide?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of gadodiamide?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects of gadodiamide may occur up to several days after injection.

Gadodiamide can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:

  • burning, itching, swelling, scaling, and tightening or hardening of your skin;
  • muscle weakness;
  • joint stiffness in your arms, hands, legs, or feet;
  • deep bone pain in your ribs or your hips;
  • trouble moving; or
  • skin redness or discoloration.

Also call your doctor at once if you have:

  • kidney problems --little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;
  • shortness of breath (even with mild exertion); or
  • chest pain or pressure, pain spreading to your jaw or shoulder.

Common side effects may include:

  • headache;
  • dizziness; or
  • nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect gadodiamide?

Other drugs may interact with gadodiamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your doctor or pharmacist can provide more information about gadodiamide.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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