Pronunciation: HYE droe KLOR oh THYE a zide and ir be SAR tan
Brand: Avalide
12.5 mg-150 mg, round, red, imprinted with 54 857
12.5 mg-300 mg, oval, yellow, imprinted with 54 948
12.5 mg-300 mg, capsule, pink, imprinted with TEVA, 7239
12.5 mg-150 mg, capsule, pink, imprinted with TEVA, 7238
12.5 mg-150 mg, oval, orange, imprinted with ML 34
12.5 mg-300 mg, oval, orange, imprinted with ML33
12.5 mg-300 mg, capsule, pink, imprinted with TEVA, 7239
12.5 mg-150 mg, capsule, pink, imprinted with 325, HH
12.5 mg-300 mg, capsule, pink, imprinted with 327, HH
12.5 mg-150 mg, oblong, peach, imprinted with 2775, LOGO HEART
12.5 mg-300 mg, oblong, peach, imprinted with 2776, LOGO HEART
You should not use this medicine if you are unable to urinate, or if you are allergic to sulfa drugs.
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.
If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine).
Hydrochlorothiazide is a diuretic (water pill). Irbesartan is an angiotensin II receptor blocker (sometimes called an ARB blocker).
Hydrochlorothiazide and irbesartan is a combination medicine used to treat high blood pressure (hypertension).
Hydrochlorothiazide and irbesartan may also be used for purposes not listed in this medication guide.
You should not use this medicine if you are allergic to irbesartan or hydrochlorothiazide, or:
If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine).
You may also need to avoid taking hydrochlorothiazide and irbesartan with aliskiren if you have kidney disease.
Tell your doctor if you have ever had:
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
You should not breastfeed while using this medicine.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take this medicine with or without food.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.
Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated.
If you need surgery or medical tests, tell the surgeon ahead of time that you are using hydrochlorothiazide and irbesartan.
It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis.
Drinking alcohol can further lower your blood pressure and may cause side effects.
Do not use potassium supplements or salt substitutes, unless your doctor has told you to.
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, this medicine can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
If you also take cholestyramine or colestipol, take your hydrochlorothiazide and irbesartan dose 4 hours before or 4 hours after you take the other medicine.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect hydrochlorothiazide and irbesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2022 Cerner Multum, Inc. Version: 11.01. Revision date: 2/15/2021.
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