Pronunciation: HYE dro KLOR oh THY a zide and spir ON oh LAK tone
25 mg-25 mg, round, tan, imprinted with ALDACTAZIDE 25, SEARLE 1011
50 mg-50 mg, oblong, tan, imprinted with ALDACTAZIDE 50, SEARLE 1021
25 mg-25 mg, round, white, imprinted with MP 40
25 mg-25 mg, round, beige, imprinted with 5014, G
25 mg-25 mg, round, white, imprinted with M 41
25 mg-25 mg, round, beige, imprinted with MP 40
Hydrochlorothiazide is a thiazide diuretic (water pill). Spironolactone is a potassium-sparing diuretic.
Hydrochlorothiazide and spironolactone is a combination medicine used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. This medicine also treats high blood pressure (hypertension), or low potassium levels (hypokalemia) caused by using a diuretic.
Do not use this medicine for any condition that has not been checked by your doctor.
Hydrochlorothiazide and spironolactone may also be used for purposes not listed in this medication guide.
You should not use this medicine if you are allergic to hydrochlorothiazide or spironolactone, or if you have:
Tell your doctor if you have ever had:
In animal studies, spironolactone caused certain types of tumors. It is not known whether tumors could occur in people using this medicine. Ask your doctor about your risk.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using this medicine.
This medicine is not approved for use by anyone younger than 18 years old.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Do not share this medicine with another person, even if they have the same symptoms you have.
You may need frequent medical tests.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using hydrochlorothiazide and spironolactone.
If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and spironolactone. You may need to stop using the medicine for a short time.
If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
Store at room temperature away from moisture and heat.
Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis.
Drinking alcohol with this medicine can cause side effects.
Do not use potassium supplements or salt substitutes, unless your doctor has told you to.
Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Using this medicine with other drugs that make you drowsy or lower your blood pressure can worsen these effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect hydrochlorothiazide and spironolactone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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