How should I take isoniazid and rifampin?
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using isoniazid and rifampin.
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take isoniazid and rifampin on an empty stomach, at least 1 hour before or 2 hours after a meal.
Isoniazid and rifampin may cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (a yellow, orange, red, or brown color). This side effect is usually not harmful. However, soft contact lenses may be permanently stained if you wear them while taking isoniazid and rifampin.
Dark colored urine can be a sign of liver problems. Call your doctor if you have reddish-brown urine together with upper stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).
Your doctor may have you take extra vitamin B6 while you are taking isoniazid and rifampin. Take only the amount of vitamin B6 that your doctor has prescribed.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Isoniazid and rifampin will not treat a viral infection such as the common cold or flu.
Isoniazid and rifampin is usually given until lab tests show that the infection has cleared.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using isoniazid and rifampin.
Store at room temperature away from moisture, heat, and light.