How should I take ivacaftor and lumacaftor?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take this medicine with food that contains fat, such as butter, peanut butter, eggs, avocados, nuts, whole milk, cheese, yogurt, or cheese pizza. Follow your doctor's dosing instructions very carefully.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
To use the oral granules: Mix the granules with 1 teaspoon of milk, juice, or soft food such as applesauce, yogurt, or pudding. The food or liquid should be at or below room temperature. Mix only 1 dose at a time, and use the mixture within 1 hour after mixing. Feed the child a high-fat food just before or just after giving the granule mixture.
Take your doses at regular intervals, 12 hours apart. This will keep a steady amount of the drug in your body at all times.
Ivacaftor and lumacaftor doses are based on age and weight in children. Children from 2 to 5 years old should take oral granules. Children 6 and older should take tablets.
You will need frequent blood tests to check your liver function. Your blood pressure may also need to be checked often.
A child using this medicine may need frequent eye exams to check for cataracts.
Store at room temperature away from moisture and heat. Keep each tablet in its daily blister strip until you are ready to take your dose.