What should I discuss with my healthcare provider before taking levomilnacipran?
You should not use this medicine if you are allergic to levomilnacipran or milnacipran (Savella).
Do not use levomilnacipran within 7 days before or 14 days after you have taken an MAO inhibitor. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.
Tell your doctor if you also use stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with levomilnacipran could cause a serious condition called serotonin syndrome.
Tell your doctor if you have ever had:
- glaucoma;
- heart problems, high blood pressure;
- a stroke;
- bleeding problems;
- urination problems;
- sexual problems;
- kidney disease;
- a seizure;
- low levels of sodium in your blood;
- bipolar disorder (manic depression);
- if there is a history of depression, manic behavior, or suicide in your family; or
- if you drink alcohol.
People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior.
Taking this medicine during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop levomilnacipran without asking your doctor.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of levomilnacipran on the baby.
If you are breastfeeding, tell your doctor if your baby is agitated or irritable and has feeding problems or trouble gaining weight.
Not approved for use by anyone younger than 18 years old.