Pronunciation: LOO ma SIR an

Brand: Oxlumo

What is the most important information I should know about lumasiran?

You may need to follow a special diet to help control your condition.

What is lumasiran?

Lumasiran is used to treat a type of hyperoxaluria (high levels of oxalate in your urine). Oxalate is a natural chemical contained in the body and in certain foods. Too much oxalate in the urine can cause kidney stones or kidney failure.

Lumasiran is for use in adults and children of all ages.

Lumasiran may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using lumasiran?

Tell your doctor if you are pregnant or breastfeeding.

How is lumasiran given?

Lumasiran is injected under the skin.

A healthcare provider will give you this injection.

Lumasiran is usually given once every 1 to 3 months.

Lumasiran doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.

You may need to follow a special diet. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your lumasiran injection.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while using lumasiran?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of lumasiran?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include pain, redness, itching, or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect lumasiran?

Other drugs may affect lumasiran, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about lumasiran.

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