Pronunciation: MY doe drin
10 mg, round, green, imprinted with G 423
2.5 mg, round, white, imprinted with E 40
5 mg, round, orange/red, imprinted with E 43
10 mg, round, gray, imprinted with E 149
2.5 mg, round, white, imprinted with US 2.5, 211
5 mg, round, pink, imprinted with US 5, 212
10 mg, round, purple, imprinted with US 10, 213
2.5 mg, round, white, imprinted with MH 1, M
5 mg, round, white, imprinted with M, MH 2
10 mg, round, white, imprinted with M, MH 3
5 mg, round, orange, imprinted with G 422
10 mg, round, blue, imprinted with APO, MID 10
2.5 mg, round, white, imprinted with APO, MID 2.5
5 mg, round, pink, imprinted with APO, MID 5
2.5 mg, round, white, imprinted with APO, MID 2 5
5 mg, round, orange, imprinted with APO, MID 5
10 mg, round, blue, imprinted with APO, MID 10
2.5 mg, round, white, imprinted with RPC 2.5, 003
5 mg, round, orange, imprinted with RPC 5.0, 004
You should not use midodrine if you have severe heart disease, overactive thyroid, an adrenal gland tumor, kidney disease, if you are unable to urinate, or if your blood pressure is high even while lying down.
Midodrine can increase blood pressure even when you are at rest. This medicine should be used only if you have severely low blood pressure that affects your daily life. Midodrine may not improve your ability to perform daily activities.
Midodrine works by constricting (narrowing) the blood vessels and increasing blood pressure.
Midodrine is used to treat low blood pressure (hypotension) that causes severe dizziness or a light-headed feeling, like you might pass out. This medicine is for use only when low blood pressure affects daily life. Midodrine may not improve your ability to perform daily activities.
Midodrine may also be used for purposes not listed in this medication guide.
You should not use midodrine if you are allergic to it, or if you have:
To make sure midodrine is safe for you, tell your doctor if you have:
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether midodrine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Midodrine is usually taken 3 times per day, with doses spaced at least 3 hours apart. Take your last dose of the day within 3 or 4 hours before bedtime.
You may take midodrine with or without food.
Take this medicine during your normal waking hours, when your are most likely to be upright and not lying down or napping. Ask your doctor about how to take this medicine if you normally lie down during the day.
Midodrine can increase your blood pressure even while you are lying down or sleeping (when blood pressure is usually lowest). Long-term high blood pressure (hypertension) can lead to serious medical problems.
Follow your doctor's instructions about the best way to position your body while you are laying down or sleeping. You may need to keep your head elevated to help prevent high blood pressure.
Your blood pressure will need to be checked before and during treatment with midodrine. Check your blood pressure while you are lying down, and check it again with your head elevated.
Your kidney and liver function may also need to be checked.
Midodrine is only part of a treatment program that may also include lifestyle changes, wearing support stockings on your legs, and possibly special medical care. Follow your doctor's instructions very closely.
Store at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
You may need to skip a dose if you will be resting or lying down for a long period of time during your normal waking hours. Talk to your doctor about how to adjust your dose schedule if needed.
Avoid taking a dose within less than 3 hours before your normal bedtime.
Ask a doctor or pharmacist before using any over-the-counter diet pills, or cough/cold medicine that contains phenylephrine or pseudoephedrine. These medicines may raise your blood pressure.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking midodrine and call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Taking midodrine with other drugs that constrict blood vessels can further increase your blood pressure. Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete. Other drugs may interact with midodrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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