mirtazapine

Pronunciation: mir TAZ a peen

Brand: Remeron, Remeron SolTab

Remeron

slide 1 of 43, Remeron,

15 mg, oval, yellow, imprinted with Organon, TZ 3

slide 1 of 43

Remeron

slide 2 of 43, Remeron,

45 mg, oval, white, imprinted with T Z 7, Organon

slide 2 of 43

Mirtazapine

slide 3 of 43, Mirtazapine,

15 mg, round, yellow, imprinted with 9 3, 7206

slide 3 of 43

Mirtazapine

slide 4 of 43, Mirtazapine,

30 mg, round, brown, imprinted with 9 3, 7207

slide 4 of 43

Mirtazapine

slide 5 of 43, Mirtazapine,

45 mg, round, white, imprinted with 7208, 93

slide 5 of 43

Mirtazapine

slide 6 of 43, Mirtazapine,

30 mg, round, brown, imprinted with E 212

slide 6 of 43

Mirtazapine

slide 7 of 43, Mirtazapine,

15 mg, round, beige, imprinted with M 515

slide 7 of 43

Mirtazapine

slide 8 of 43, Mirtazapine,

30 mg, round, beige, imprinted with M 530

slide 8 of 43

Mirtazapine

slide 9 of 43, Mirtazapine,

45 mg, round, beige, imprinted with M 545

slide 9 of 43

Mirtazapine

slide 10 of 43, Mirtazapine,

15 mg, oblong, white, imprinted with 11 17, WPI

slide 10 of 43

Mirtazapine

slide 11 of 43, Mirtazapine,

30 mg, oval, yellow, imprinted with WPI 1118

slide 11 of 43

Mirtazapine

slide 12 of 43, Mirtazapine,

45 mg, oval, white, imprinted with WPI 1119

slide 12 of 43

Mirtazapine

slide 13 of 43, Mirtazapine,

7.5 mg, capsule, white, imprinted with A, 11

slide 13 of 43

Mirtazapine

slide 14 of 43, Mirtazapine,

30 mg, capsule, brown, imprinted with 0 9, A

slide 14 of 43

Mirtazapine

slide 15 of 43, Mirtazapine,

15 mg, capsule, yellow, imprinted with 0 8, A

slide 15 of 43

Mirtazapine

slide 16 of 43, Mirtazapine,

45 mg, capsule, white, imprinted with 10, A

slide 16 of 43

Mirtazapine

slide 17 of 43, Mirtazapine,

30 mg, oval, brown, imprinted with A, 0 9

slide 17 of 43

Mirtazapine

slide 18 of 43, Mirtazapine,

15 mg, round, beige, imprinted with M 515

slide 18 of 43

Mirtazapine

slide 19 of 43, Mirtazapine,

30 mg, round, beige, imprinted with M 530

slide 19 of 43

Mirtazapine

slide 20 of 43, Mirtazapine,

15 mg, oval, yellow, imprinted with 499

slide 20 of 43

Mirtazapine

slide 21 of 43, Mirtazapine,

30 mg, oval, brown, imprinted with 500

slide 21 of 43

Mirtazapine

slide 22 of 43, Mirtazapine,

15 mg, oval, yellow, imprinted with APO, MI 15

slide 22 of 43

Mirtazapine

slide 23 of 43, Mirtazapine,

30 mg, oval, pink, imprinted with APO, MI 30

slide 23 of 43

Mirtazapine

slide 24 of 43, Mirtazapine,

45 mg, oval, white, imprinted with APO, MI-45

slide 24 of 43

Mirtazapine

slide 25 of 43, Mirtazapine,

30 mg, capsule, red, imprinted with A, 09

slide 25 of 43

Mirtazapine

slide 26 of 43, Mirtazapine,

15 mg, oblong, yellow, imprinted with A, 8 0

slide 26 of 43

Mirtazapine

slide 27 of 43, Mirtazapine,

45 mg, oblong, white, imprinted with A, 10

slide 27 of 43

Mirtazapine

slide 28 of 43, Mirtazapine,

15 mg, round, white, imprinted with TZ 1

slide 28 of 43

Mirtazapine

slide 29 of 43, Mirtazapine,

30 mg, round, white, imprinted with TZ 2

slide 29 of 43

Mirtazapine

slide 30 of 43, Mirtazapine,

15 mg, round, blue, imprinted with b 241

slide 30 of 43

Mirtazapine

slide 31 of 43, Mirtazapine,

15 mg, round, white, citrus, imprinted with 7303, 93

slide 31 of 43

Mirtazapine

slide 32 of 43, Mirtazapine,

15 mg, oblong, yellow, imprinted with A, 8 0

slide 32 of 43

Mirtazapine

slide 33 of 43, Mirtazapine,

15 mg, round, yellow, imprinted with E 20

slide 33 of 43

Mirtazapine

slide 34 of 43, Mirtazapine,

30 mg, round, blue, imprinted with b 242

slide 34 of 43

Mirtazapine

slide 35 of 43, Mirtazapine,

30 mg, round, white, citrus, imprinted with 7304, 93

slide 35 of 43

Mirtazapine

slide 36 of 43, Mirtazapine,

15 mg, round, white, imprinted with 2469, WPI

slide 36 of 43

Mirtazapine

slide 37 of 43, Mirtazapine,

45 mg, round, white, imprinted with 2471, WPI

slide 37 of 43

Mirtazapine

slide 38 of 43, Mirtazapine,

45 mg, round, white, imprinted with E 222

slide 38 of 43

Remeron

slide 39 of 43, Remeron,

15 mg, elliptical, yellow, imprinted with Organon, TZ 3

slide 39 of 43

Remeron

slide 40 of 43, Remeron,

30 mg, elliptical, pink, imprinted with Organon, TZ 5

slide 40 of 43

Remeron SolTab

slide 41 of 43, Remeron SolTab,

15 mg, round, white, imprinted with T Z 1

slide 41 of 43

Remeron SolTab

slide 42 of 43, Remeron SolTab,

30 mg, round, white, imprinted with T Z 2

slide 42 of 43

Remeron SolTab

slide 43 of 43, Remeron SolTab,

45 mg, round, white, imprinted with T Z 4

slide 43 of 43

What is the most important information I should know about mirtazapine?

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

What is mirtazapine?

Mirtazapine is an antidepressant that is used to treat major depressive disorder.

Mirtazapine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking mirtazapine?

You should not take this medicine if you are allergic to mirtazapine.

Do not use mirtazapine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have ever had:

liver or kidney disease;
seizures or epilepsy;
bipolar disorder (manic depression);
heart problems;
long QT syndrome (in you or a family member); or
low blood pressure or dizzy spells.

Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with mirtazapine and cause a serious condition called serotonin syndrome.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

The orally disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

How should I take mirtazapine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take the medicine at the same time each day, usually at bedtime.

Take the regular tablet form of mirtazapine with water.

You may take mirtazapine with or without food.

Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet on your tongue and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.

It may take a few weeks for your symptoms to improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.

Do not stop using mirtazapine suddenly, or you could have unpleasant withdrawal symptoms (such as dizziness, vomiting, anxiety, confusion, strange dreams, feeling shaky). Ask your doctor how to safely stop using mirtazapine.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include confusion, memory problems, drowsiness, and fast heart rate.

What should I avoid while taking mirtazapine?

Drinking alcohol with this medicine can cause side effects.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

What are the possible side effects of mirtazapine?

Get emergency medical help if you have signs of an allergic reaction (hives, joint pain, fever, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

feeling restless or being unable to sit still;
racing thoughts, decreased need for sleep, unusual risk-taking behavior, feelings of extreme happiness or sadness, being more talkative than usual;
blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
a light-headed feeling, like you might pass out;
fever, chills, sore throat, mouth sores;
changes in weight or appetite;
severe rash, blisters, or swelling on the palms of your hands or the soles of your feet;
a seizure; or
low sodium level --headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects include:

drowsiness, dizziness;
strange dreams;
dry mouth;
constipation;
increased appetite; or
weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mirtazapine?

Using mirtazapine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Tell your doctor about all your current medicines. Many drugs can affect mirtazapine, especially:

cimetidine;
diazepam;
St. John's wort;
tramadol;
tryptophan (sometimes called L-tryptophan);
an antibiotic --clarithromycin, rifampin, rifampicin, telithromycin;
antifungal medicine --itraconazole, ketoconazole;
antiviral medicine to treat HIV/AIDS --indinavir, nelfinavir, ritonavir, saquinavir;
medicine to treat mood disorders, thought disorders, or mental illness --such as lithium, other antidepressants, or antipsychotics;
migraine headache medicine --sumatriptan, rizatriptan, Imitrex, Maxzalt, and others; or
seizure medicine --carbamazepine, phenytoin.

This list is not complete and many other drugs may affect mirtazapine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about mirtazapine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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