What are the possible side effects of obinutuzumab?
Get emergency medical help if you have signs of an allergic reaction: hives, rash; fever, joint pain; fast heartbeats, chest pain, wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.
Obinutuzumab may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
Some side effects may occur during the injection, or within 24 hours afterward. Tell your caregiver if you feel sudden warmth, redness, tingly feeling, feverish, chilled, light-headed, nauseated, or if you have headache, pounding in your neck or ears, tiredness, rash, dizziness, diarrhea, vomiting, chest discomfort, or trouble breathing.
Call your doctor at once if you have other side effects such as:
- easy bruising, unusual bleeding, purple or red spots under your skin;
- weakness, cough, diarrhea, burning when you urinate;
- right-sided upper stomach pain, loss of appetite, yellowing of your skin or eyes;
- dizziness, loss of balance or coordination;
- confusion, vision problems, problems with speech or walking;
- low white blood cell counts --fever, mouth sores, skin sores, sore throat, cough, trouble breathing; or
- signs of tumor cell breakdown --tiredness, muscle cramps, nausea, vomiting, fast or slow heart rate, tingling in your hands and feet or around your mouth.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- a reaction during or shortly after the injection;
- tiredness;
- low white blood cell counts;
- diarrhea, constipation;
- muscle or joint pain; or
- cold symptoms such as stuffy nose, sneezing, cough, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.