Pronunciation: on DAN se tron
Brand: Zofran, Zofran ODT, Zuplenz
4 mg, round, white, imprinted with M, 315
8 mg, round, orange, imprinted with M, 344
4 mg, round, white, imprinted with M, 732
8 mg, round, white, imprinted with M, 734
4 mg, round, white, imprinted with GG, 927
8 mg, round, yellow, imprinted with GG, 928
4 mg, round, white, imprinted with R, 153
8 mg, round, yellow, imprinted with R, 154
4 mg, round, white, imprinted with 5, E
4 mg, oval, white, imprinted with 130
8 mg, oval, yellow, imprinted with 131
8 mg, oval, white, imprinted with 241
8 mg, oval, yellow, imprinted with 8, NO
4 mg, round, white, strawberry, imprinted with 5, E
8 mg, round, white, strawberry, imprinted with 7, E
4 mg, oval, white, imprinted with 4, NO
4 mg, round, white, imprinted with G, 4
8 mg, round, white, imprinted with G, 8
4 mg, round, white, imprinted with 93, 7301
4 mg, round, white, imprinted with 93, 233
8 mg, round, white, imprinted with 93, 7302
8 mg, round, yellow, imprinted with 93, 7236
4 mg, round, white, imprinted with 5, E
4 mg, oval, white, strawberry, imprinted with 240
4 mg, oval, white, imprinted with Zofran, 4
8 mg, oval, yellow, imprinted with Zofran, 8
Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting.
Ondansetron is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment.
Ondansetron may be used for purposes not listed in this medication guide.
You should not use ondansetron if:
To make sure ondansetron is safe for you, tell your doctor if you have:
Ondansetron is not expected to harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Ondansetron is not approved for use by anyone younger than 4 years old.
Ondansetron orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Ondansetron can be taken with or without food.
The first dose of ondansetron is usually taken before the start of your surgery, chemotherapy, or radiation treatment. Follow your doctor's dosing instructions very carefully.
Take the ondansetron regular tablet with a full glass of water.
To take the orally disintegrating tablet (Zofran ODT):
To use ondansetron oral soluble film (strip) (Zuplenz):
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Store at room temperature away from moisture, heat, and light. Store liquid medicine in an upright position.
Get emergency medical help if you have signs of an allergic reaction: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Ondansetron can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ondansetron.
Taking ondansetron while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called "serotonin syndrome," which can be fatal. Tell your doctor if you also use:
This list is not complete and many other drugs can interact with ondansetron. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2022 Cerner Multum, Inc. Version: 13.01. Revision date: 10/21/2016.
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