What is the most important information I should know about quinapril?
Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.
You should not use quinapril if you have ever had angioedema. Do not take quinapril within 36 hours before or after taking medicine that contains sacubatril (such as Entresto).
If you have diabetes, do not use quinapril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).
What is quinapril?
Quinapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.
Quinapril is used to treat high blood pressure (hypertension) and heart failure.
Quinapril may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking quinapril?
You should not use quinapril if you are allergic to it, or if:
- you have a history of angioedema;
- you recently took a heart medicine called sacubatril; or
- if you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, ramipril, or trandolapril.
Do not take quinapril within 36 hours before or after taking medicine that contains sacubatril (such as Entresto).
If you have diabetes, do not use quinapril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).
You may also need to avoid taking quinapril with aliskiren if you have kidney disease.
To make sure quinapril is safe for you, tell your doctor if you have ever had:
- kidney disease (or if you are on dialysis);
- liver disease;
- a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis;
- heart disease or congestive heart failure (unless you are taking quinapril for this condition); or
- if you are on a low-salt diet.
Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Quinapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
Quinapril can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take quinapril?
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your blood pressure will need to be checked often. Your kidney or liver function may also need to be tested.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking quinapril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.
If you need surgery, tell the surgeon ahead of time that you are using quinapril. You may need to stop using the medicine for a short time.
If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking quinapril?
Do not use salt substitutes or potassium supplements while taking quinapril, unless your doctor has told you to.
Drinking alcohol can further lower your blood pressure and may increase certain side effects of quinapril.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
What are the possible side effects of quinapril?
Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- a light-headed feeling, like you might pass out;
- fast or pounding heartbeats, fluttering in your chest;
- little or no urination;
- pain or burning when you urinate;
- jaundice (yellowing of the skin or eyes);
- numbness, tingling, or burning pain in your hands or feet;
- fever, chills, cold or flu symptoms;
-
high potassium --nausea, slow or unusual heart rate, weakness, loss of movement; or
-
low sodium --headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.
Common side effects may include:
- headache;
- cough; or
- dizziness, tired feeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect quinapril?
Tell your doctor about all your current medicines and any you start or stop using, especially:
- lithium;
- a diuretic or "water pill";
- gold injections to treat arthritis; or
-
NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may interact with quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Where can I get more information?
Your pharmacist can provide more information about quinapril.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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