How is ravulizumab given?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
If you've been using another drug called eculizumab (Soliris), you will need to wait 2 weeks after your last dose of eculizumab before starting treatment with ravulizumab.
Ravulizumab is injected into a vein by a healthcare provider. The first two infusions are usually given 2 weeks apart, followed by an infusion once every 4-8 weeks.
After each infusion, you will be watched closely for at least 1 hour to make sure you do not have an allergic reaction.
Doses are based on weight. Your dose may change if you gain or lose weight.
You may get infections more easily, even serious or fatal infections. You will need frequent medical tests.
Read the Patient Safety Card about serious infections and the symptoms to watch for. Keep this card with you at all times while using ravulizumab and for at least 8 months after your last dose. Your infection risk could last for several months after you stop using ravulizumab.
Some people may have an increased risk of gonorrhea (a sexually transmitted disease). Talk with your doctor about safe ways to keep from getting an infection during sex.
Ravulizumab can have long lasting effects on your body, even after you stop using this medicine. If you have PNH and you stop using ravulizumab, your doctor may need to check your progress for at least 16 weeks after your last dose. If you have aHUS and you stop using ravulizumab, your doctor may need to check you for at least 12 months after your last dose.