ropinirole (oral)

Pronunciation: roe PIN i role

Brand: Requip, Requip XL

ROPINIRole Hydrochloride

slide 1 of 43, ROPINIRole Hydrochloride,

0.25 mg, round, white, imprinted with 54 511

slide 1 of 43

ROPINIRole Hydrochloride

slide 2 of 43, ROPINIRole Hydrochloride,

0.5 mg, round, yellow, imprinted with 54 337

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ROPINIRole Hydrochloride

slide 3 of 43, ROPINIRole Hydrochloride,

1 mg, round, green, imprinted with 54 751

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ROPINIRole Hydrochloride

slide 4 of 43, ROPINIRole Hydrochloride,

2 mg, round, peach, imprinted with 54 231

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ROPINIRole Hydrochloride

slide 5 of 43, ROPINIRole Hydrochloride,

3 mg, round, red, imprinted with 54 575

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ROPINIRole Hydrochloride

slide 6 of 43, ROPINIRole Hydrochloride,

4 mg, round, brown, imprinted with 54 273

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ROPINIRole Hydrochloride

slide 7 of 43, ROPINIRole Hydrochloride,

5 mg, round, blue, imprinted with 54 722

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ROPINIRole Hydrochloride ER

slide 8 of 43, ROPINIRole Hydrochloride ER,

6 mg, oval, white, imprinted with 640

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ROPINIRole Hydrochloride ER

slide 9 of 43, ROPINIRole Hydrochloride ER,

2 mg, oval, pink, imprinted with 658

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ROPINIRole Hydrochloride ER

slide 10 of 43, ROPINIRole Hydrochloride ER,

12 mg, oval, yellow, imprinted with 661

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ROPINIRole Hydrochloride

slide 11 of 43, ROPINIRole Hydrochloride,

5 mg, round, blue, imprinted with M, N 50

slide 11 of 43

ROPINIRole Hydrochloride

slide 12 of 43, ROPINIRole Hydrochloride,

0.25 mg, round, white, imprinted with 972, HH

slide 12 of 43

ROPINIRole Hydrochloride

slide 13 of 43, ROPINIRole Hydrochloride,

0.5 mg, round, yellow, imprinted with 973, HH

slide 13 of 43

ROPINIRole Hydrochloride

slide 14 of 43, ROPINIRole Hydrochloride,

1 mg, round, green, imprinted with 974, HH

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ROPINIRole Hydrochloride

slide 15 of 43, ROPINIRole Hydrochloride,

2 mg, round, pink, imprinted with 975, HH

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ROPINIRole Hydrochloride

slide 16 of 43, ROPINIRole Hydrochloride,

3 mg, round, purple, imprinted with 976, HH

slide 16 of 43

ROPINIRole Hydrochloride

slide 17 of 43, ROPINIRole Hydrochloride,

4 mg, round, brown, imprinted with 977, HH

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ROPINIRole Hydrochloride

slide 18 of 43, ROPINIRole Hydrochloride,

5 mg, round, blue, imprinted with 978, HH

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Requip

slide 19 of 43, Requip,

0.25 mg, pentagonal, white, imprinted with 4890, SB

slide 19 of 43

Requip

slide 20 of 43, Requip,

0.5 mg, pentagonal, yellow, imprinted with 4891, SB

slide 20 of 43

Requip

slide 21 of 43, Requip,

1 mg, pentagonal, green, imprinted with 4892, SB

slide 21 of 43

Requip

slide 22 of 43, Requip,

2 mg, pentagonal, pink, imprinted with 4893, SB

slide 22 of 43

Requip

slide 23 of 43, Requip,

3 mg, pentagonal, purple, imprinted with 4895, SB

slide 23 of 43

Requip

slide 24 of 43, Requip,

4 mg, pentagonal, brown, imprinted with 4896, SB

slide 24 of 43

Requip

slide 25 of 43, Requip,

5 mg, pentagonal, blue, imprinted with 4894, SB

slide 25 of 43

Requip XL

slide 26 of 43, Requip XL,

12 mg, oval, green, imprinted with GS, YX7

slide 26 of 43

Requip XL

slide 27 of 43, Requip XL,

2 mg, oval, pink, imprinted with GS, 3V2

slide 27 of 43

Requip XL

slide 28 of 43, Requip XL,

4 mg, oval, brown, imprinted with GS, WXG

slide 28 of 43

Requip XL

slide 29 of 43, Requip XL,

8 mg, oval, red, imprinted with GS, 5CC

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Requip XL

slide 30 of 43, Requip XL,

6 mg, oblong, white, imprinted with GS, 11F

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ROPINIRole Hydrochloride

slide 31 of 43, ROPINIRole Hydrochloride,

0.25 mg, round, white, imprinted with M, N25

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ROPINIRole Hydrochloride

slide 32 of 43, ROPINIRole Hydrochloride,

0.25 mg, round, white, imprinted with 9 3, 5282

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ROPINIRole Hydrochloride

slide 33 of 43, ROPINIRole Hydrochloride,

0.5 mg, round, green, imprinted with M, N 5

slide 33 of 43

ROPINIRole Hydrochloride

slide 34 of 43, ROPINIRole Hydrochloride,

0.5 mg, round, yellow, imprinted with 9 3, 5283

slide 34 of 43

ROPINIRole Hydrochloride

slide 35 of 43, ROPINIRole Hydrochloride,

1 mg, round, green, imprinted with M, N10

slide 35 of 43

ROPINIRole Hydrochloride

slide 36 of 43, ROPINIRole Hydrochloride,

1 mg, round, yellow, imprinted with 9 3, 5284

slide 36 of 43

ROPINIRole Hydrochloride

slide 37 of 43, ROPINIRole Hydrochloride,

2 mg, round, peach, imprinted with M, N 20

slide 37 of 43

ROPINIRole Hydrochloride

slide 38 of 43, ROPINIRole Hydrochloride,

2 mg, round, peach, imprinted with 9 3, 5285

slide 38 of 43

ROPINIRole Hydrochloride

slide 39 of 43, ROPINIRole Hydrochloride,

3 mg, round, lavender, imprinted with M, N30

slide 39 of 43

ROPINIRole Hydrochloride

slide 40 of 43, ROPINIRole Hydrochloride,

3 mg, round, red, imprinted with 9 3, 5286

slide 40 of 43

ROPINIRole Hydrochloride

slide 41 of 43, ROPINIRole Hydrochloride,

4 mg, round, white, imprinted with M, N 40

slide 41 of 43

ROPINIRole Hydrochloride

slide 42 of 43, ROPINIRole Hydrochloride,

4 mg, round, tan, imprinted with 9 3, 5287

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ROPINIRole Hydrochloride

slide 43 of 43, ROPINIRole Hydrochloride,

5 mg, round, blue, imprinted with 9 3, 5288

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What is the most important information I should know about ropinirole?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is ropinirole?

Ropinirole has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease.

Ropinirole is used to treat symptoms of Parkinson's disease (stiffness, tremors, muscle spasms, and poor muscle control). Ropinirole is also used to treat restless legs syndrome (RLS).

Only immediate-release ropinirole (Requip) is approved to treat either Parkinson symptoms or RLS. Extended-release ropinirole (Requip XL) is approved only to treat Parkinson symptoms.

Parkinson's and RLS are two separate disorders. Having one of these conditions will not cause you to have the other condition.

Ropinirole may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking ropinirole?

You should not use ropinirole if you are allergic to it.

To make sure ropinirole is safe for you, tell your doctor if you have:

high or low blood pressure;
kidney disease (or if you are on dialysis);
heart disease, heart rhythm problems;
a sleep disorder such as narcolepsy, or other conditions that may cause daytime sleepiness; or
if you smoke.

People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether ropinirole passes into breast milk or if it could affect the nursing baby. Ropinirole may slow breast milk production. Tell your doctor if you are breast-feeding.

Ropinirole is not approved for use by anyone younger than 18 years old.

How should I take ropinirole?

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.

If you are taking immediate-release ropinirole (Requip) you should not take extended-release ropinirole (Requip XL) at the same time.

The dose and timing of ropinirole in treating Parkinson's disease is different from the dose and timing in treating RLS. Follow the directions on your prescription label. Ask your pharmacist if you have any questions about the kind of ropinirole you receive at the pharmacy.

Ropinirole can be taken with or without food. Take the medicine at the same time each day.

Do not crush, chew, or break an extended-release tablet (Requip XL). Swallow it whole.

Call your doctor if you see part of the ropinirole tablet in your stool. This is a sign that your body may not have absorbed all of the medicine.

If you are taking this medicine for RLS, tell your doctor if your symptoms get worse, if they occur in the morning or earlier than usual in the evening, or if you feel restless symptoms in your hands or arms.

It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Do not stop using ropinirole suddenly, or you could have unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking ropinirole?

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Dizziness may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.

Drinking alcohol can increase certain side effects of ropinirole.

What are the possible side effects of ropinirole?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Some people taking ropinirole have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.

Call your doctor at once if you have:

extreme drowsiness, falling asleep suddenly (even after feeling alert);
worsening or no improvement in your symptoms;
a light-headed feeling, like you might pass out;
unusual changes in mood or behavior;
tremors, twitching uncontrollable muscle movements; or
hallucinations (seeing or hearing things that are not real).

Side effects such as confusion or hallucinations may be more likely in older adults.

Common side effects may include:

drowsiness, dizziness, weakness;
headache, confusion, hallucinations;
increased blood pressure (severe headache, pounding in your neck or ears, nosebleed, irregular heartbeats);
nausea, vomiting, upset stomach, constipation;
flu symptoms (fever, chills, body aches);
sudden muscle movements;
increased sweating; or
swelling in your legs or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ropinirole?

Taking ropinirole with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, narcotic medication, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with ropinirole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about ropinirole.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2020 Cerner Multum, Inc. Version: 14.01. Revision date: 3/27/2017.

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