How should I take selumetinib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take selumetinib with a full glass of water on an empty stomach, at least 1 hour before or 2 hours after a meal.
Take the medicine at the same time each day, about every 12 hours. Follow your doctor's dosing instructions very carefully.
Swallow the capsule whole and do not crush, chew, break, or open it.
Tell your doctor if the child taking selumetinib has trouble swallowing the capsule whole.
If you vomit shortly after taking selumetinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
Tell your doctor if you start having loose stools. You may be given anti-diarrhea medicine. Keep using this medicine for as long as your doctor has prescribed.
Drink plenty of liquids if you have diarrhea.
Selumetinib can cause your heart to pump less blood than normal. Your heart function will need to be checked every 3 to 6 months while you are taking this medicine.
Selumetinib can also cause eye problems that may lead to blindness. You will need frequent vision exams, and your next dose may be delayed based on the results.
Selumetinib doses are based on body surface area (height and weight). Your dose needs may change if you gain or lose weight or if you are still growing.
Do not change your dose or dosing schedule without your doctor's advice.
Store at room temperature away from moisture and heat. Keep the capsules in their original container, along with the packet or canister of moisture-absorbing preservative.