telotristat ethyl

Pronunciation: tel OH tri stat ETH il

Brand: Xermelo

What is the most important information I should know about telotristat ethyl?

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

What is telotristat ethyl?

Telotristat ethyl is used in adults to treat carcinoid syndrome diarrhea, in combination with another medicine such as octreotide (Sandostatin).

Telotristat ethyl may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking telotristat ethyl?

Tell your doctor if you have ever had liver disease.

Tell your doctor if you are pregnant or breastfeeding.

Not approved for use by anyone younger than 18 years old.

How should I take telotristat ethyl?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Telotristat ethyl is usually taken 3 times per day with food.

Telotristat ethyl comes in a monthly case that contains 4 weekly boxes; 1 box of 7 daily doses for use each week. Keep each tablet in the package until you are ready to take a dose.

Octreotide is usually given at least 30 minutes after taking telotristat ethyl.

Telotristat ethyl is only part of a complete treatment program that may also include other medications. Do not change your doses or medication schedule without your doctor's advice.

Store at room temperature away from moisture and heat.

Do not share this medicine with another person, even if they have the same symptoms you have.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking telotristat ethyl?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of telotristat ethyl?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using telotristat ethyl and call your doctor at once if you have:

  • severe constipation; or
  • severe or worsening stomach pain.

Common side effects may include:

  • nausea, loss of appetite, gas;
  • headache, depressed mood;
  • swelling in your hands or feet;
  • fever; or
  • abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect telotristat ethyl?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect telotristat ethyl, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Your pharmacist can provide more information about telotristat ethyl.

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