Pronunciation: TEM oh ZOE loe mide
100 mg, capsule, pink/white, imprinted with TEMODAR, 100 mg logo
250 mg, capsule, white, imprinted with TEMODAR, 250mg logo
140 mg, capsule, blue/white, imprinted with TEMODAR, 140 MG
180 mg, capsule, orange/white, imprinted with TEMODAR, 180 mg
20 mg, capsule, white/yellow, imprinted with TEMODAR, 20 mg
5 mg, capsule, green/white, imprinted with TEMODAR, logo 5mg
140 mg, capsule, blue/white, imprinted with 140mg
20 mg, capsule, yellow/white, imprinted with 20mg
250 mg, capsule, white, imprinted with 250mg
You should not use temozolomide if you are allergic to it, or to dacarbazine.
Tell your doctor if you have ever had:
Using temozolomide may increase your risk of developing certain types of bone marrow cancer. Ask your doctor about your specific risk.
You may need to have a negative pregnancy test before starting this treatment.
Temozolomide can harm an unborn baby if the mother or the father is using this medicine.
This medicine may affect fertility (ability to have children) in men. Talk to your doctor about your own risk.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Temozolomide is given in a 28-day treatment cycle, and you may only need to take the medicine during the first few days of each cycle.
If you are also receiving radiation treatment, you may need to take temozolomide for 6 to 7 weeks in a row during your first treatment cycle. Then you may be switched to a 28-day maintenance treatment cycle.
Your doctor may occasionally change your dose to make sure you get the best results. The size, color, and number of temozolomide capsules you take may sometimes be different from earlier treatment cycles. Be sure you know the correct number of capsules to take and on which days to take them. Ask your doctor or pharmacist if you have any questions.
Temozolomide doses are based on body surface area (height and weight). Your dose needs may change if you gain or lose weight or if you are still growing.
Take all of your capsules for the day (one entire daily dose) at the same time on each dosing day of a treatment cycle. Swallow the capsules whole with a full glass of water.
Take this medicine at the same time each day.
Swallow the capsule whole and do not crush, chew, break, or open it.
You may take temozolomide with or without food, but take it the same way each time.
Your doctor will determine how long to treat you with temozolomide. Follow your doctor's dosing instructions very carefully.
You may need to take temozolomide at bedtime or on an empty stomach if the medicine upsets your stomach.
If you vomit shortly after taking the medicine, do not take another capsule until your next regularly scheduled dose.
Do not use an open capsule. The medicine from a broken pill can be dangerous if it gets in your mouth, eyes, or nose, or on your skin. If this happens, wash your skin with soap and water or rinse your eyes with water. Ask your pharmacist how to safely dispose of a broken pill.
You may be given medication to prevent nausea or other side effects while you are receiving temozolomide.
Temozolomide can increase your risk of bleeding or infection. You will need frequent medical tests. Your cancer treatments may be delayed based on the results.
Your liver function may also need to be checked during treatment and for 2 to 4 weeks after you stop using this medicine.
Store temozolomide at room temperature away from moisture and heat.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Men should not donate semen while using temozolomide and for at least 90 days after the last dose.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect temozolomide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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