How should I take tolcapone?
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using tolcapone.
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Do not take tolcapone as your only Parkinson's medication. Tolcapone must be used in combination with carbidopa and levodopa.
Tolcapone is usually taken three times a day. The first dose is taken with your first daily dose of carbidopa and levodopa. The second and third doses of tolcapone are taken 6 and 12 hours later.
Follow your doctor's dosing instructions very carefully.
Tolcapone may be taken with or without food.
Tolcapone may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.
Your liver function will need to be checked often: Every 2 to 4 weeks for the first 6 months of treatment, and then as often as your doctor recommends.
Call your doctor if your symptoms do not improve after 3 weeks of treatment.
Do not stop using tolcapone suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using tolcapone.
Store at room temperature in a tightly closed container, away from moisture and heat.