What is the most important information I should know about vardenafil?
Some medicines can cause unwanted or dangerous effects when used with vardenafil. Tell your doctor about all your medicines, especially riociguat (Adempas).
Do not take vardenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking vardenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Stop using vardenafil and get emergency medical help if you have sudden vision loss.
What is vardenafil?
Vardenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.
Vardenafil is used to treat erectile dysfunction (impotence).
Vardenafil may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking vardenafil?
You should not use vardenafil if you are allergic to it, or if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).
Vardenafil is not approved for men younger than 18 years old.
Do not take vardenafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking vardenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
Tell your doctor if you have ever had:
- heart disease, heart rhythm problems;
- a heart attack, stroke, or congestive heart failure;
- long QT syndrome (in you or a family member);
- high or low blood pressure;
- seizures;
- liver disease, kidney disease (or if you are on dialysis);
- a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
- a bleeding disorder such as hemophilia;
- a stomach ulcer;
- hearing or vision problems, vision loss;
- an eye disorder such as retinitis pigmentosa (an inherited condition of the eye);
- a physical deformity of the penis (such as Peyronie's disease); or
- if you have been told you should not have sexual intercourse for health reasons.
Vardenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether vardenafil is the actual cause of vision loss.
Staxyn may contain phenylalanine. Talk to your doctor before using this form of vardenafil if you have phenylketonuria (PKU).
Vardenafil is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown.
How should I take vardenafil?
Staxyn (vardenafil disintegrating tablets) should not be used in place of Levitra (vardenafil regular tablets). Avoid medication errors by using only the form and strength your doctor prescribes.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Vardenafil can be taken with or without food.
Remove an orally disintegrating (Staxyn) tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve without chewing. Swallow several times as the tablet dissolves. Do not take Staxyn with liquid.
Vardenafil is taken only when needed, about 60 minutes before sexual activity. The medicine can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Store at room temperature away from moisture and heat.
If you receive medical care for heart problems, tell your caregivers when you last took vardenafil.
What happens if I miss a dose?
Since vardenafil is used as needed, you are not likely to be on a dosing schedule.
Do not take vardenafil more than once a day. Allow 24 hours to pass between doses.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking vardenafil?
Grapefruit may interact with vardenafil and lead to unwanted side effects. Avoid the use of grapefruit products.
Drinking alcohol can increase certain side effects of vardenafil.
Do not use any other drug to treat impotence unless your doctor tells you to.
What are the possible side effects of vardenafil?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking vardenafil and get emergency medical help if you have:
-
heart attack symptoms --chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
- vision changes or sudden vision loss; or
- erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis).
Stop using vardenafil and call your doctor at once if you have:
- ringing in your ears, or sudden hearing loss;
- irregular heartbeat;
- swelling in your hands, ankles, or feet;
- shortness of breath;
- a light-headed feeling, like you might pass out;
- penis erection that is painful or lasts 4 hours or longer; or
- seizure (convulsions).
Common side effects may include:
- flushing (warmth, redness, or tingly feeling);
- stuffy nose, sinus pain;
- headache, dizziness;
- upset stomach; or
- back pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect vardenafil?
Do not take vardenafil with similar medications such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). Tell your doctor about all other medications you use for erectile dysfunction.
Tell your doctor about all your other medicines, especially:
-
an antibiotic --clarithromycin, erythromycin;
-
antifungal medicine --itraconazole, ketoconazole;
-
drugs to treat high blood pressure or a prostate disorder --alfuzosin, doxazosin, prazosin, silodosin, terazosin, tamsulosin;
-
heart rhythm medicine --amiodarone, dronedarone, procainamide, quinidine, sotalol; or
-
HIV/AIDS medicine --atazanavir, indinavir, ritonavir, saquinavir, and others.
This list is not complete and many other drugs may affect vardenafil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Where can I get more information?
Your pharmacist can provide more information about vardenafil.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2020 Cerner Multum, Inc. Version: 11.02. Revision date: 11/5/2018.
