zanamivir

What is the most important information I should know about zanamivir?

What is zanamivir?

Zanamivir is an antiviral medicine that blocks the actions of viruses in your body.

Zanamivir is used to treat flu symptoms caused by influenza virus in people who have had symptoms for less than 2 days. Zanamivir may also be given to prevent influenza in people who may be exposed but do not yet have symptoms. Zanamivir will not treat the common cold.

Zanamivir should not be used in place of getting a yearly flu shot. The Centers for Disease Control recommends an annual flu shot to help protect you each year from new strains of influenza virus.

Zanamivir may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using zanamivir?

Tell your doctor if you have ever had:

• asthma, chronic obstructive pulmonary disease (COPD), or any other chronic lung condition.

It is not known whether this medicine will harm an unborn baby. However, getting sick with influenza during pregnancy can cause complications leading to birth defects, low birth weight, preterm delivery, or stillbirth. Your doctor will decide whether you should use zanamivir if you are pregnant.

The Centers for Disease Control and Prevention (CDC) recommends that pregnant women may receive a yearly flu vaccine to prevent influenza. Zanamivir is not to be used in place of the yearly flu shot.

How should I use zanamivir?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Start taking zanamivir as soon as possible after flu symptoms appear, such as fever, chills, muscle aches, sore throat, and runny or stuffy nose.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Zanamivir is packaged in disk-shaped foil packs that contain 4 blisters of medicine. These disks are placed into a device called a DISKHALER that you will use to inhale the medicine. The device opens and loads a blister of zanamivir each time you use the inhaler.

To treat flu symptoms: Use 2 inhalations twice per day for 5 days. On the first day of treatment, space your doses at least 2 hours apart. On the following days, space your doses at least 12 hours apart.

To prevent flu symptoms: Use 2 inhalations every 24 hours for 10 to 28 days. Follow your doctor's instructions.

Do not use a nebulizer or ventilator to give zanamivir. Zanamivir inhalation powder should never be mixed with a liquid.

If you are scheduled to use a bronchodilator at the same time as zanamivir, use the bronchodilator first.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 2 hours. Do not use two doses at one time.

What happens if I overdose?

What should I avoid while using zanamivir?

What are the possible side effects of zanamivir?

• sudden confusion;
• trouble speaking;
• tremors or shaking;
• a seizure; or
• hallucinations (hearing or seeing things that are not there).

Common side effects may include:

• headache, dizziness;
• nausea, vomiting, diarrhea;
• cough, wheezing, trouble breathing;
• ear pain; or
• cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect zanamivir?

Other drugs may affect zanamivir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about zanamivir.