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Glucosamine and Chondroitin
Glucosamine and Chondroitin
Treatment Overview
Glucosamine and chondroitin are part of normal cartilage. Cartilage acts as a cushion between the bones in a joint.
These supplements come in tablet, capsule, powder, or liquid form. They are often taken together or taken with other supplements. Glucosamine may be taken separately as a dietary supplement for joints.
Glucosamine
Glucosamine, also called chitosamine, is a natural substance that comes from the covering of shellfish. Or it can be made in a lab. It's also known as:
- Glucosamine hydrochloride.
- N-acetyl-glucosamine (NAG).
- Glucosamine sulfate. This is a combination of glucosamine and mineral salt.
The body absorbs glucosamine well.
Chondroitin
Chondroitin can come from natural sources, such as shark or bovine cartilage. Or it can be made in a lab. It's also known as:
- Chondroitin sulfate. This is a combination of chondroitin and mineral salt.
- Chondroitin sulfuric acid.
- Chonsurid.
Why It Is Used
Why It Is Used
Many people take glucosamine and chondroitin, alone or together, for osteoarthritis. Some people believe they help. But an analysis of studies looking at glucosamine or chondroitin for arthritis in the hip or knee did not show that these supplements slow joint damage or relieve pain.footnote 1
Risks
Risks
It appears that glucosamine and chondroitin, alone or together, are safe and have few side effects. But they cost money and will not help you more than a placebo (fake pill). Talk to your doctor if you are thinking about taking these supplements.
If you are allergic to shellfish, do not take glucosamine unless you have talked to your doctor. Some glucosamine is made from shellfish covering.
The U.S. Food and Drug Administration does not regulate dietary supplements in the same way it regulates medicines. A dietary supplement can be sold with limited or no research on how well it works.
References
References
Citations
- Wandel S, et al. (2010). Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of the hip or knee: Network meta-analysis. BMJ. Published online September 16, 2010. DOI: 10.1136/bmj.c4675).
Current as of: July 31, 2024
Author: Ignite Healthwise, LLC Staff
Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.
This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.
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© 2024 Ignite Healthwise, LLC. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Ignite Healthwise, LLC.
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