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Home Knowledge Center Wellness Library acetaminophen and oxycodone

acetaminophen and oxycodone

Pronunciation: a SEET a MIN oh fen and OX i KOE done

Brand: Endocet 10/325, Endocet 2.5/325, Endocet 5/325, Endocet 7.5/325, Nalocet, Percocet, Primlev

Roxicet

slide 1 of 27, Roxicet,

325 mg-5 mg, round, white, imprinted with 54 543

Image of Roxicet
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Acetaminophen-Oxycodone Hydrochloride

slide 2 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with 512

Image of Acetaminophen-Oxycodone Hydrochloride
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Acetaminophen-Oxycodone Hydrochloride

slide 3 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with 4839, V

Image of Acetaminophen-Oxycodone Hydrochloride
slide 3 of 27

Endocet 5/325

slide 4 of 27, Endocet 5/325,

325 mg-5 mg, round, white, imprinted with Endo 602

Image of Endocet 5/325
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Percocet 5/325

slide 5 of 27, Percocet 5/325,

325 mg-5 mg, round, blue, imprinted with PERCOCET 5

Image of Percocet 5/325
slide 5 of 27

Percocet

slide 6 of 27, Percocet,

325 mg-2.5 mg, oval, pink, imprinted with 2.5, PERCOCET

Image of Percocet
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Percocet 7.5/325

slide 7 of 27, Percocet 7.5/325,

325 mg-7.5 mg, oval, orange, imprinted with PERCOCET, 7.5/325

Image of Percocet 7.5/325
slide 7 of 27

Percocet 10/325

slide 8 of 27, Percocet 10/325,

325 mg-10 mg, capsule, yellow, imprinted with 10/325, PERCOCET

Image of Percocet 10/325
slide 8 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 9 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with 555 278

Image of Acetaminophen-Oxycodone Hydrochloride
slide 9 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 10 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-7.5 mg, capsule, white, imprinted with IP207

Image of Acetaminophen-Oxycodone Hydrochloride
slide 10 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 11 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-10 mg, oval, white, imprinted with 10/325, M523

Image of Acetaminophen-Oxycodone Hydrochloride
slide 11 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 12 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with IP, 203

Image of Acetaminophen-Oxycodone Hydrochloride
slide 12 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 13 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with 512

Image of Acetaminophen-Oxycodone Hydrochloride
slide 13 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 14 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-7.5 mg, oval, white, imprinted with 7.5/325, M522

Image of Acetaminophen-Oxycodone Hydrochloride
slide 14 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 15 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-7.5 mg, oval, white, imprinted with U16

Image of Acetaminophen-Oxycodone Hydrochloride
slide 15 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 16 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-10 mg, capsule, white, imprinted with U17

Image of Acetaminophen-Oxycodone Hydrochloride
slide 16 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 17 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-10 mg, round, white, imprinted with 10;325, RP

Image of Acetaminophen-Oxycodone Hydrochloride
slide 17 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 18 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with A 349

Image of Acetaminophen-Oxycodone Hydrochloride
slide 18 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 19 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with 5;325, R;P

Image of Acetaminophen-Oxycodone Hydrochloride
slide 19 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 20 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-7.5 mg, round, white, imprinted with 7.5;325, RP

Image of Acetaminophen-Oxycodone Hydrochloride
slide 20 of 27

Endocet 10/325

slide 21 of 27, Endocet 10/325,

325 mg-10 mg, capsule, yellow, imprinted with 10/325, E712

Image of Endocet 10/325
slide 21 of 27

Endocet 7.5/325

slide 22 of 27, Endocet 7.5/325,

325 mg-7.5 mg, oval, orange, imprinted with 7.5/325, E700

Image of Endocet 7.5/325
slide 22 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 23 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-10 mg, round, white, imprinted with WATSON 932

Image of Acetaminophen-Oxycodone Hydrochloride
slide 23 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 24 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-5 mg, round, white, imprinted with WATSON 749

Image of Acetaminophen-Oxycodone Hydrochloride
slide 24 of 27

Acetaminophen-Oxycodone Hydrochloride

slide 25 of 27, Acetaminophen-Oxycodone Hydrochloride,

325 mg-7.5 mg, round, white, imprinted with WATSON 933

Image of Acetaminophen-Oxycodone Hydrochloride
slide 25 of 27

Percocet 5/325

slide 26 of 27, Percocet 5/325,

325 mg-5 mg, round, blue, imprinted with PERCOCET 5

Image of Percocet 5/325
slide 26 of 27

Roxicet

slide 27 of 27, Roxicet,

325 mg-5 mg, round, white, imprinted with 54 543

Image of Roxicet
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What is the most important information I should know about acetaminophen and oxycodone?

What is the most important information I should know about acetaminophen and oxycodone?

MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.

Taking opioid medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.

Fatal side effects can occur if you use opioid medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

What is acetaminophen and oxycodone?

What is acetaminophen and oxycodone?

Acetaminophen and oxycodone is a combination medicine used to relieve moderate to severe pain.

Acetaminophen and oxycodone contains an opioide medicine and may be habit-forming.

Acetaminophen and oxycodone may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking acetaminophen and oxycodone?

What should I discuss with my healthcare provider before taking acetaminophen and oxycodone?

You should not use this medicine if you are allergic to acetaminophen or oxycodone, or if you have:

  • severe asthma or breathing problems; or
  • a blockage in your stomach or intestines.

Tell your doctor if you have ever had:

  • breathing problems, sleep apnea;
  • liver disease;
  • a drug or alcohol addiction;
  • kidney disease;
  • a head injury or seizures;
  • urination problems; or
  • problems with your thyroid, pancreas, or gallbladder.

If you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.

Ask a doctor before using opioid medicine if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

How should I take acetaminophen and oxycodone?

How should I take acetaminophen and oxycodone?

Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. An overdose can damage your liver or cause death. Tell your doctor if you feel an increased urge to use more of this medicine.

Never share opioid medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine in a place where others cannot get to it. Selling or giving away opioid medicine is against the law.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

If you need surgery or medical tests, tell the doctor ahead of time that you are using this medicine.

You should not stop using this medicine suddenly. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.

What happens if I miss a dose?

What happens if I miss a dose?

Since this medicine is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of this medicine can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include nausea, vomiting, sweating, severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

What should I avoid while taking acetaminophen and oxycodone?

What should I avoid while taking acetaminophen and oxycodone?

Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Do not drink alcohol. Dangerous side effects or death could occur.

Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen (sometimes abbreviated as APAP). Taking certain medications together can lead to a fatal overdose.

What are the possible side effects of acetaminophen and oxycodone?

What are the possible side effects of acetaminophen and oxycodone?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing, breathing that stops;
  • a light-headed feeling, like you might pass out;
  • weakness, tiredness, fever, unusual bruising or bleeding;
  • confusion, unusual thoughts or behavior;
  • problems with urination;
  • liver problems --nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • low cortisol levels -- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or
  • high levels of serotonin in the body --agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.

Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.

Common side effects include:

  • dizziness, drowsiness, feeling tired;
  • feelings of extreme happiness or sadness;
  • nausea, vomiting, stomach pain;
  • constipation; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect acetaminophen and oxycodone?

What other drugs will affect acetaminophen and oxycodone?

You may have breathing problems or withdrawal symptoms if you start or stop taking certain other medicines. Tell your doctor if you also use an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C.

Opioid medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

  • cold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic ("water pill");
  • medicines for motion sickness, irritable bowel syndrome, or overactive bladder;
  • other opioids --opioid pain medicine or prescription cough medicine;
  • a sedative like Valium --diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and others;
  • drugs that make you sleepy or slow your breathing --a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness;
  • drugs that affect serotonin levels in your body --a stimulant, or medicine for depression, Parkinson's disease, migraine headaches, serious infections, or nausea and vomiting.

This list is not complete. Other drugs may affect acetaminophen and oxycodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about acetaminophen and oxycodone.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

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