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argatroban

Pronunciation: ar GAT roe ban

What is the most important information I should know about argatroban?

What is the most important information I should know about argatroban?

You should not use this medicine if you have any major bleeding from a surgery, injury, or other cause.

Argatroban can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have unusual bruising, or bleeding that will not stop.

What is argatroban?

What is argatroban?

Argatroban blocks the activity of certain clotting substances in the blood.

Argatroban is used to treat or prevent blood clots in adults who have thrombocytopenia (low levels of platelets in the blood) caused by using heparin. Argatroban is sometimes used in people who are undergoing a procedure called angioplasty (to open blocked arteries).

Argatroban may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving argatroban?

What should I discuss with my health care provider before receiving argatroban?

You should not use argatroban if you are allergic to it, or if you have any major bleeding from a surgery, injury, or other cause.

Tell your doctor if you have ever had:

  • a stomach ulcer or bleeding;
  • liver disease;
  • a bleeding or blood clotting disorder (such as hemophilia);
  • severe or uncontrolled high blood pressure;
  • a spinal tap or epidural anesthesia; or
  • major surgery (especially eye surgery, brain surgery, or spinal cord surgery).

Taking argatroban during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant while taking argatroban.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Argatroban is not approved for use by anyone younger than 18 years old.

How is argatroban given?

How is argatroban given?

Argatroban is given as an infusion into a vein. A healthcare provider will give you this injection.

Argatroban is given until your blood coagulates properly. Your doctor will test your blood often to determine how long to treat you with argatroban.

Argatroban can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have unusual bruising, or bleeding that will not stop.

What happens if I miss a dose?

What happens if I miss a dose?

Since argatroban is given by a healthcare professional, you are not likely to miss a dose.

What happens if I overdose?

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving argatroban?

What should I avoid while receiving argatroban?

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Avoid alcohol. It may increase your risk of bleeding in your stomach or intestines.

What are the possible side effects of argatroban?

What are the possible side effects of argatroban?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • easy bruising or bleeding (nosebleeds, bleeding gums, heavy menstrual bleeding);
  • unexpected pain or swelling;
  • any bleeding that will not stop;
  • a light-headed feeling, like you might pass out;
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • urine that looks red, pink, or brown;
  • slow heart rate, weak pulse, fainting, slow breathing (breathing may stop); or
  • signs of infection --fever, flu symptoms, mouth and throat ulcers, rapid heart rate, shallow breathing.

Common side effects may include:

  • infection;
  • problems with heart function;
  • fever;
  • nausea, vomiting, diarrhea;
  • low blood pressure;
  • shortness of breath;
  • headache, back pain; or
  • chest pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect argatroban?

What other drugs will affect argatroban?

Tell your doctor about all your other medicines, especially other medicines to treat or prevent blood clots.

Other drugs may affect argatroban, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your doctor or pharmacist can provide more information about argatroban.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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