Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library articaine and epinephrine

articaine and epinephrine

Pronunciation: AR ti kane and EP i NEF rin

Brand: Septocaine

What is the most important information I should know about articaine and epinephrine?

What is the most important information I should know about articaine and epinephrine?

You should not receive articaine and epinephrine if you have ever had an allergic reaction to any type of numbing medicine.

What is articaine and epinephrine?

What is articaine and epinephrine?

Articaine and epinephrine are anesthetics (numbing medicines). They work by blocking nerve signals in your body.

Articaine and epinephrine is a combination medicine used to numb your mouth for a dental procedure.

Articaine and epinephrine may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving articaine and epinephrine?

What should I discuss with my health care provider before receiving articaine and epinephrine?

You should not receive this medicine if you are allergic to any type of numbing medicine.

To make sure articaine and epinephrine is safe for you, tell your doctor if you have:

  • a heart rhythm disorder;
  • low or high blood pressure;
  • asthma or a sulfite allergy; or
  • a history of seizures.

FDA pregnancy category C. It is not known whether articaine and epinephrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether articaine and epinephrine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How is articaine and epinephrine given?

How is articaine and epinephrine given?

Articaine and epinephrine is given as an injection that is usually placed into the gum area inside your mouth. You will receive this injection in a dentist's office or oral surgical setting.

What happens if I miss a dose?

What happens if I miss a dose?

Since articaine and epinephrine is given as needed before a dental procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme drowsiness, fainting, seizure (convulsions), shallow breathing, or slow heart rate.

What should I avoid after receiving articaine and epinephrine?

What should I avoid after receiving articaine and epinephrine?

This medication can cause numbness for an extended period of time. Avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

What are the possible side effects of articaine and epinephrine?

What are the possible side effects of articaine and epinephrine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling or puffiness of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • weak or shallow breathing;
  • a slow heart rate;
  • a light-headed feeling, like you might pass out;
  • blurred vision, ringing in your ears; or
  • anxiety, confusion, restless feeling, or tremors.

Call your doctor or dentist at once if you have any swelling, pain, or heavy bleeding after your procedure.

Common side effects may include:

  • tongue pain or swelling, red or swollen gums;
  • mild swelling in your face;
  • headache; or
  • numbness and tingling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect articaine and epinephrine?

What other drugs will affect articaine and epinephrine?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with articaine and epinephrine, especially:

  • an antidepressant-- amitriptylline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, trimipramine;
  • antipsychotic medication --chlorpromazine, droperidol, fluphenazine, haloperidol, perphenazine; or
  • an MAO inhibitor --isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This list is not complete. Other drugs may interact with articaine and epinephrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Where can I get more information?

Your dentist or pharmacist can provide more information about articaine and epinephrine.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details