Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library cefuroxime (oral/injection)

cefuroxime (oral/injection)

Pronunciation: SEF ue ROX eem

Cefuroxime Axetil

slide 1 of 20, Cefuroxime Axetil,

250 mg, oval, white, imprinted with A33

Image of Cefuroxime Axetil
slide 1 of 20

Cefuroxime Axetil

slide 2 of 20, Cefuroxime Axetil,

250 mg, oval, white, imprinted with A33

Image of Cefuroxime Axetil
slide 2 of 20

Cefuroxime Axetil

slide 3 of 20, Cefuroxime Axetil,

500 mg, capsule, white, imprinted with A34

Image of Cefuroxime Axetil
slide 3 of 20

Cefuroxime Axetil

slide 4 of 20, Cefuroxime Axetil,

500 mg, capsule, blue, imprinted with 203

Image of Cefuroxime Axetil
slide 4 of 20

Cefuroxime Axetil

slide 5 of 20, Cefuroxime Axetil,

250 mg, oval, white, imprinted with LUPIN, 302

Image of Cefuroxime Axetil
slide 5 of 20

Cefuroxime Axetil

slide 6 of 20, Cefuroxime Axetil,

500 mg, oval, white, imprinted with LUPIN, 303

Image of Cefuroxime Axetil
slide 6 of 20

Ceftin

slide 7 of 20, Ceftin,

250 mg, oblong, blue, imprinted with Glaxo, 387

Image of Ceftin
slide 7 of 20

Ceftin

slide 8 of 20, Ceftin,

500 mg, oblong, blue, imprinted with Glaxo, 394

Image of Ceftin
slide 8 of 20

Cefuroxime Axetil

slide 9 of 20, Cefuroxime Axetil,

250 mg, capsule, blue, imprinted with 250, P125

Image of Cefuroxime Axetil
slide 9 of 20

Cefuroxime Axetil

slide 10 of 20, Cefuroxime Axetil,

250 mg, oblong, white, imprinted with LUPIN, 302

Image of Cefuroxime Axetil
slide 10 of 20

Cefuroxime Axetil

slide 11 of 20, Cefuroxime Axetil,

250 mg, oblong, blue, imprinted with RX 751

Image of Cefuroxime Axetil
slide 11 of 20

Cefuroxime Axetil

slide 12 of 20, Cefuroxime Axetil,

250 mg, oblong, blue, imprinted with RX 751

Image of Cefuroxime Axetil
slide 12 of 20

Cefuroxime Axetil

slide 13 of 20, Cefuroxime Axetil,

250 mg, oblong, white, imprinted with 302, LUPIN

Image of Cefuroxime Axetil
slide 13 of 20

Cefuroxime Axetil

slide 14 of 20, Cefuroxime Axetil,

250 mg, oblong, white, imprinted with W921

Image of Cefuroxime Axetil
slide 14 of 20

Cefuroxime Axetil

slide 15 of 20, Cefuroxime Axetil,

500 mg, capsule, blue, imprinted with 500, P126

Image of Cefuroxime Axetil
slide 15 of 20

Cefuroxime Axetil

slide 16 of 20, Cefuroxime Axetil,

500 mg, oblong, white, imprinted with APO, C500

Image of Cefuroxime Axetil
slide 16 of 20

Cefuroxime Axetil

slide 17 of 20, Cefuroxime Axetil,

500 mg, oblong, blue, imprinted with RX752

Image of Cefuroxime Axetil
slide 17 of 20

Cefuroxime Axetil

slide 18 of 20, Cefuroxime Axetil,

500 mg, oblong, white, imprinted with 303, LUPIN

Image of Cefuroxime Axetil
slide 18 of 20

Cefuroxime Axetil

slide 19 of 20, Cefuroxime Axetil,

500 mg, capsule, white, imprinted with W 922

Image of Cefuroxime Axetil
slide 19 of 20

Cefuroxime Axetil

slide 20 of 20, Cefuroxime Axetil,

500 mg, oblong, blue, imprinted with RX752

Image of Cefuroxime Axetil
slide 20 of 20
What is the most important information I should know about cefuroxime?

What is the most important information I should know about cefuroxime?

Cefuroxime can cause serious or life-threatening allergic reactions. Tell your doctor if you have an allergy to an antibiotic, especially penicillin.

What is cefuroxime?

What is cefuroxime?

Cefuroxime is a cephalosporin (SEF a low spor in) antibiotic that is used to treat bacterial infections of the ear, nose, throat, lungs, skin, bones, joints, bladder, or kidneys. Cefuroxime is also used to treat gonorrhea, sepsis, or early Lyme disease.

Cefuroxime injection is sometimes given before and after a surgery to prevent infection.

Cefuroxime may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using cefuroxime?

What should I discuss with my healthcare provider before using cefuroxime?

Cefuroxime can cause serious or life-threatening allergic reactions. You should not use this medicine if you have ever had a severe allergic reaction to an antibiotic, such as:

  • cefuroxime, cefadroxil, cefdinir, cefoxitin, cefprozil, ceftriaxone, cephalexin, Keflex, Omnicef, and others;
  • avibactam, relebactam, sulbactam, tazobactam, vaborbactam, and others; or
  • amoxicillin (Amoxil, Augmentin, Moxatag), ampicillin, dicloxacillin, oxacillin, penicillin, and others.

Tell your doctor if you have ever had:

  • an stomach or intestinal disorder such as colitis;
  • kidney disease;
  • liver disease; or
  • heart problems.

Cefuroxime oral suspension may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Tell your doctor if you are pregnant or breastfeeding.

If you are being treated for gonorrhea: Having gonorrhea during pregnancy may increase the risk of complications including premature birth, low birth weight, or gonorrhea developing the newborn. The benefit of treating this condition may outweigh any risks to the baby.

Not approved for use by anyone younger than 3 months old.

How should I use cefuroxime?

How should I use cefuroxime?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Cefuroxime oral is taken by mouth.

Swallow the tablet whole and do not crush, chew, or break it. Take with or without food.

Shake the oral suspension (liquid). Measure a dose with the supplied measuring device (not a kitchen spoon). Take with food.

Tell your doctor if a child taking cefuroxime has trouble swallowing the medicine.

Cefuroxime oral may be given as a single dose to treat gonorrhea. For most other infections, cefuroxime oral is usually given for 7 to 10 days, or for 20 days to treat early Lyme disease.

Your dose needs may change if you switch from tablets to oral suspension. Follow your doctor's dosing instructions very carefully.

Cefuroxime injection is given into a muscle or a vein, usually for 5 to 10 days.

Ask your doctor or pharmacist if you don't understand how to use an injection.

You may need to mix cefuroxime with a liquid (diluent) before using it. Use only the diluent your doctor has recommended.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine has changed colors or has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Keep using this medicine even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication. Cefuroxime will not treat a viral infection (flu or a common cold).

Cefuroxime can affect the results of certain medical tests. Tell any doctor who treats you that you are using cefuroxime.

Store the tablets at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Store the oral suspension in the refrigerator, do not freeze. Throw away any unused medicine after 10 days.

After mixing cefuroxime for injection, you will need to use it within a certain number of hours or days. This will depend on the diluent and how you store the mixture (at room temperature or in a refrigerator). Be sure you understand how to properly mix and store the medicine if using injections at home.

If the cefuroxime injection is frozen when you receive it, thaw the medicine at room temperature (do not use heat).

After thawing, you may store the cefuroxime injection at room temperature for up to 24 hours, or in a refrigerator for up to 7 days. Do not refreeze the medicine once it has been thawed.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use take doses at one time.

Call your doctor for instructions if you miss a cefuroxime injection.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include seizure.

What should I avoid while using cefuroxime?

What should I avoid while using cefuroxime?

Antibiotic medicines can cause diarrhea. Tell your doctor if you have diarrhea that is watery or bloody.

What are the possible side effects of cefuroxime?

What are the possible side effects of cefuroxime?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
  • jaundice (yellowing of the skin or eyes);
  • fever, chills;
  • a seizure; or
  • chest pain.

Common side effects may include:

  • nausea, vomiting, diarrhea;
  • flu-like symptoms;
  • vaginal itching or discharge; or
  • diaper rash (in people using the oral suspension).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect cefuroxime?

What other drugs will affect cefuroxime?

Tell your doctor about all your other medicines, especially:

  • any other IV antibiotic;
  • probenecid;
  • a diuretic or "water pill";
  • a blood thinner --warfarin, Coumadin, Jantoven; or
  • a stomach acid reducer --esomeprazole, famotidine, Nexium, Pepcid, Prevacid, Prilosec, Tagamet, Zantac, and others.

This list is not complete. Other drugs may affect cefuroxime, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about cefuroxime.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details