Skip to main navigation Skip to main content Skip to footer For Medicare For Providers For Brokers For Employers Español For Individuals & Families: For Individuals & Families Medical Dental Other Supplemental Explore coverage through work How to Buy Health Insurance Types of Dental Insurance Open Enrollment vs. Special Enrollment See all topics Shop for Medicare plans Member Guide Find a Doctor Log in to myCigna
Home Knowledge Center Wellness Library ceritinib

ceritinib

Pronunciation: se RI ti nib

Brand: Zykadia

What is the most important information I should know about ceritinib?

What is the most important information I should know about ceritinib?

Ceritinib can harm an unborn baby. Both men and women using this medicine should use effective birth control to prevent pregnancy. Keep using birth control for at least 6 months after your last dose of ceritinib if you are a woman, or 3 months after your last dose if you are a man.

Tell your doctor if you have severe or ongoing stomach symptoms (nausea, vomiting, diarrhea, stomach pain).

Ceritinib can cause serious side effects on your heart, lungs, or liver. Call your doctor right away if you have: right-sided-stomach pain, loss of appetite, bruising or bleeding, dark urine, yellowing of your skin or eyes, fever, cough, chest pain, irregular heartbeats, shortness of breath, or sudden dizziness.

What is ceritinib?

What is ceritinib?

Ceritinib is used to treat non-small cell lung cancer that has spread to other parts of the body.

Ceritinib is used only if your cancer has a specific genetic marker. Your doctor will test you for this gene.

Ceritinib may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking ceritinib?

What should I discuss with my healthcare provider before taking ceritinib?

You should not use ceritinib if you are allergic to it.

Tell your doctor if you have ever had:

  • heart problems;
  • long QT syndrome (in you or a family member);
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
  • a pancreas disorder;
  • diabetes or high blood sugar; or
  • liver disease.

Ceritinib can harm an unborn baby if the mother or the father is taking this medicine.

  • If you are a woman, do not use ceritinib if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
  • If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
  • Tell your doctor right away if a pregnancy occurs while either the mother or the father is using ceritinib.

You should not breast-feed while using this medicine and for at least 2 weeks after your last dose.

How should I take ceritinib?

How should I take ceritinib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Ceritinib is usually taken once per day with food. Follow your doctor's dosing instructions very carefully.

If you vomit shortly after taking ceritinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.

You may be given medication to prevent nausea or vomiting while you are receiving ceritinib.

You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.

Ceritinib is usually given until your body no longer responds to the medication.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 12 hours. Do not use two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking ceritinib?

What should I avoid while taking ceritinib?

Grapefruit may interact with ceritinib and lead to unwanted side effects. Avoid the use of grapefruit products.

What are the possible side effects of ceritinib?

What are the possible side effects of ceritinib?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Ceritinib usually causes side effects on your stomach (nausea, vomiting, diarrhea, stomach pain) that can be severe. Call your doctor if you have severe or ongoing stomach symptoms.

Also call your doctor at once if you have:

  • severe pain in your upper stomach spreading to your back;
  • slow heartbeats, weak pulse, weak or shallow breathing;
  • sudden chest pain or discomfort, fever, dry cough or cough with mucus, feeling short of breath;
  • fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
  • high blood sugar --increased thirst, increased urination, hunger, fruity breath odor, headaches, thinking problems, blurred vision, feeling tired; or
  • high blood sugar --increased thirst, increased urination, dry mouth, fruity breath odor; o
  • liver problems --right-sided-stomach pain, loss of appetite, unusual tiredness, itching, easy bruising or bleeding, dark urine, or yellowing of the skin or eyes.

Common side effects may include:

  • stomach pain, loss of appetite;
  • nausea, vomiting, diarrhea;
  • feeling tired; or
  • weight loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ceritinib?

What other drugs will affect ceritinib?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect ceritinib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about ceritinib.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

<cipublic-spinner variant="large"><span>Loading…</span></cipublic-spinner>

Page Footer

I want to...

Get an ID card File a claim View my claims and EOBs Check coverage under my plan See prescription drug list Find an in-network doctor, dentist, or facility Find a form Find 1095-B tax form information View the Cigna Glossary Contact Cigna

Audiences

Individuals and Families Medicare Employers Brokers Providers

Secure Member Sites

myCigna member portal Health Care Provider portal Cigna for Employers Client Resource Portal Cigna for Brokers

Cigna Company Information

About Cigna Company Profile Careers Newsroom Investors Suppliers Third Party Administrators International Evernorth

 Cigna. All rights reserved.

Privacy Legal Product Disclosures Cigna Company Names Customer Rights Accessibility Non-Discrimination Notice [PDF] Language Assistance [PDF] Report Fraud Sitemap

Disclaimer

Individual and family medical and dental insurance plans are insured by Cigna Health and Life Insurance Company (CHLIC), Cigna HealthCare of Arizona, Inc., Cigna HealthCare of Illinois, Inc., and Cigna HealthCare of North Carolina, Inc. Group health insurance and health benefit plans are insured or administered by CHLIC, Connecticut General Life Insurance Company (CGLIC), or their affiliates (see a listing of the legal entities  that insure or administer group HMO, dental HMO, and other products or services in your state). Accidental Injury, Critical Illness, and Hospital Care plans or insurance policies are distributed exclusively by or through operating subsidiaries of Cigna Corporation, are administered by Cigna Health and Life Insurance Company, and are insured by either (i) Cigna Health and Life Insurance Company (Bloomfield, CT); (ii) Life Insurance Company of North America (“LINA”) (Philadelphia, PA); or (iii) New York Life Group Insurance Company of NY (“NYLGICNY”) (New York, NY), formerly known as Cigna Life Insurance Company of New York. The Cigna name, logo, and other Cigna marks are owned by Cigna Intellectual Property, Inc. LINA and NYLGICNY are not affiliates of Cigna.

All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico.

Selecting these links will take you away from Cigna.com to another website, which may be a non-Cigna website. Cigna may not control the content or links of non-Cigna websites. Details