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Home Knowledge Center Wellness Library diroximel fumarate

diroximel fumarate

Pronunciation: dye ROX i mel FUE ma rate

Brand: Vumerity

What is the most important information I should know about diroximel fumarate?

What is the most important information I should know about diroximel fumarate?

You should not use this medicine if you have had a severe allergic reaction to diroximel fumarate, or if you also use dimethyl fumarate (Tecfidera).

What is diroximel fumarate?

What is diroximel fumarate?

Diroximel fumarate is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).

Diroximel fumarate may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking diroximel fumarate?

What should I discuss with my healthcare provider before taking diroximel fumarate?

You should not use this medicine if:

  • you have had a severe allergic reaction to diroximel fumarate or dimethyl fumarate (Tecfidera); or
  • you also use dimethyl fumarate.

Tell your doctor if you have ever had:

  • liver disease;
  • kidney disease;
  • infections; or
  • low white blood cell (WBC) counts.

Tell your doctor if you are pregnant or breastfeeding.

Diroximel fumarate is not approved for use by anyone younger than 18 years old.

How should I take diroximel fumarate?

How should I take diroximel fumarate?

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using diroximel fumarate.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Swallow the capsule whole and do not crush, chew, break, or open it.

If you take diroximel fumarate with food, avoid foods that are high in calories or fat. Your meal or snack should not contain more than 700 calories or more than 30 grams of fat.

Do not drink alcohol when you take your diroximel fumarate dose.

Diroximel fumarate may cause flushing (a sudden sense of warmth or tingling), which should decrease over time. If this side effect is bothersome, ask your doctor about taking aspirin to help prevent flushing.

Store at room temperature away from moisture and heat.

Diroximel fumarate can have long lasting effects on your body. You may need frequent medical tests while using this medicine and for a short time after your last dose.

What happens if I miss a dose?

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking diroximel fumarate?

What should I avoid while taking diroximel fumarate?

Avoid high-fat, high-calorie meals or snacks while taking diroximel fumarate to reduce certain side effects.

What are the possible side effects of diroximel fumarate?

What are the possible side effects of diroximel fumarate?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Diroximel fumarate may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.

Also call your doctor at once if you have:

  • liver problems --loss of appetite, stomach pain (upper right side), tiredness, dark urine, jaundice (yellowing of the skin or eyes);
  • signs of infection --fever, chills, sweating, cough, shortness of breath, headache, neck stiffness, increased sensitivity to light, nausea, vomiting; or
  • symptoms of herpes virus --flu-like symptoms, cold sores around your mouth, tingly or painful blistering rash, burning pain in your thigh or lower back.

Common side effects may include:

  • indigestion, nausea, vomiting, stomach pain;
  • skin rash, itching, or redness;
  • diarrhea; or
  • flushing (sudden warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect diroximel fumarate?

What other drugs will affect diroximel fumarate?

Other drugs may affect diroximel fumarate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Where can I get more information?

Your pharmacist can provide more information about diroximel fumarate.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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